首页|中药联合肠内营养在AECOPD并发营养不良患者中的应用效果及价值

中药联合肠内营养在AECOPD并发营养不良患者中的应用效果及价值

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目的 观察益肺健脾方联合肠内营养对慢性阻塞性肺疾病急性加重期伴营养不良患者的疗效.方法 前瞻性选取2015年6月~2016年8月呼吸内科收治的120例被确诊为AECOPD伴营养不良患者,采用随机数字表法将其分为EN组和联合组,每组60例,EN组应用高脂低糖EN液+ω-3鱼油脂肪乳+丙氨酰谷氨酰胺,联合组在EN组基础上加益肺健脾冲剂,对比2组患者营养状况、免疫功能改善情况.结果 2组患者均顺利完成14d治疗,治疗后BMI、TSF、MAMC、TP、ALB、PA、HGB、TFN、NB水平较治疗前均明显提高(P均<0.05),联合组治疗后各项指标水平均明显高于EN组(P均<0.05);2组患者治疗后WBC、hs-CRP、IL-6、TNF-α水平较治疗前明显降低,TLC、IgA、IgG水平较治疗前明显增高(P均<0.05);联合组WBC、hs-CRP、IL-6、TNF-α水平低于EN组,TLC、IgA、IgG水平高于EN组(P均<0.05).结论 益肺健脾中药联合肠内营养支持可明显改善慢性阻塞性肺疾病急性加重期伴营养不良患者营养状况、呼吸功能及免疫功能,具有极高的应用价值.
Effect and value of traditional Chinese medicine combined with enteral nutrition in AECOPD patients with malnutrition
Objective To observe the curative effect of nourishing the lung and strengthening the spleen and nourishing the lung to the acute exacerbation of chronic obstructive pulmonary disease with malnutrition.MethodsProspective selection 120 cases were diagnosed as AECOPD patients with malnutrition of the Department of respiratory medicine from June 2015 to August 2016,Were randomly divided into EN group and combination group, 60 cases in each group, EN group with high fat and low sugar EN liquid Omega and ω3 Yu You Zhi Fang Ru Zhu She Ye and N(2)-L-alanyl-L-glutamine for Injection, Combined group in the EN group based on the added benefits of lung spleen, compared the Nutritional status and immune function between the two groups.ResultsTwo groups of patients were successfully completed 14d treatment, After treatment, BMI, TSF, MAMC, TP, ALB, PA, HGB, TFN, NB levels were significantly higher than those before treatment (P<0.05);Combined group after treatment, the level of each index was significantly higher than the EN group (P<0.05).WBC, hs-CRP, IL-6, TNF-α levels in the two groups were significantly lower than before treatment, TLC, IgA, and IgG levels were significantly higher than before treatment (P<0.05);the combination group WBC, hs-CRP, IL-6, TNF-αlevel lower than the EN group, TLC, IgA, IgG level higher than the EN group (P<0.05).ConclusionBenefit lung and spleen strengthening traditional Chinese medicine combined with enteral nutrition can improve the nutritional status, respiratory function and immune function in patients with acute exacerbation of chronic obstructive pulmonary disease, and has high application value.

chronic obstructive pulmonary diseaseacute exacerbationmalnutritionenteral nutritionbenefit lung and spleen

林松媚、钟静静

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文成县疾病预防控制中心,浙江 温州 325300

慢性阻塞性肺疾病 急性加重期 营养不良 肠内营养 益肺健脾方

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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