中国生化药物杂志2017,Vol.37Issue(6) :104-105.DOI:10.3969/j.issn.1005-1678.2017.06.038

疏肝通络方对乳腺癌术后上肢肿胀的临床研究

Clinical study on the effect of Shugan Tongluo Decoction on upper limb swelling after breast cancer surgery

赵铮铮 葛震
中国生化药物杂志2017,Vol.37Issue(6) :104-105.DOI:10.3969/j.issn.1005-1678.2017.06.038

疏肝通络方对乳腺癌术后上肢肿胀的临床研究

Clinical study on the effect of Shugan Tongluo Decoction on upper limb swelling after breast cancer surgery

赵铮铮 1葛震2
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作者信息

  • 1. 浙江省台州恩泽医疗中心(集团)台州医院 普外科,浙江 临海 317000
  • 2. 浙江省临海市葛震中医诊所,浙江 临海 317000
  • 折叠

摘要

目的 研究应用疏肝通络方治疗乳腺癌手术后上肢肿胀的患者,并探究治疗有效率.方法 选取2015年6月~12月在临海市葛震中医诊所就诊的84例乳腺癌患者,随机分为对照组和观察组,对照组采用β-七叶皂苷钠及常规康复治疗方案,观察组则在此基础上联合应用疏肝通络方,并对比治疗有效性.结果 观察组的治疗有效率为92.8%,明显优于对照组的78.6%(P<0.05).与此同时,观察组的VAS评分、IL-6评分和CCL-18评分均低于对照组,EORTC QLQ评分则高于对照组,治疗反馈更好(P<0.05).观察组不良反应发生率为4.7%,对照组则为9.5%,观察组治疗的安全性更高.结论 采用疏肝通络方治疗乳腺癌手术后上肢肿胀问题具有良好的缓解效果,安全性高,患者满意度良好.

Abstract

Objective To study the effect of Shugan Tongluo Recipe on the patients with upper limb swelling after breast cancer surgery, and to explore the efficiency of treatment.Methods84 patients with breast cancer were selected from June to December 2015 in the traditional Chinese medicine clinic of Ge zhen,, were randomly divided into control group and observation group, control group using beta seven yezao sodium and conventional rehabilitation therapy, observation group based on the combined application of Shugan Tongluo Decoction, and compared the effectiveness of treatment.ResultsThe effective rate of the observation group was 92.8%, significantly better than the control group 78.6%, the difference between the two groups significantly, with statistical significance (P<0.05).At the same time, the observation group VAS score, IL-6 score and CCL-18 score were lower than the control group, EORTC QLQ score is higher than that of the control group, the treatment of feedback better(P<0.05).In addition, the incidence of adverse reactions was 4.7%, 9.5% in the control group, the observation group treatment.ConclusionThe prescription of Shugan Tongluo decoction has a good effect on the treatment of upper limb swelling after breast cancer surgery, and it has high safety and good patient satisfaction.

关键词

疏肝通络方/乳腺癌手术/上肢肿胀/β-七叶皂苷钠/常规康复治疗

Key words

Shugan Tongluo Decoction/breast cancer surgery/upper limb swelling/sodium aescinate/routine rehabilitation therapy

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量2
参考文献量6
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