首页|清热疏肝退黄汤治疗初诊乙肝伴黄疸的临床观察

清热疏肝退黄汤治疗初诊乙肝伴黄疸的临床观察

扫码查看
目的 研究清热疏肝退黄汤治疗初诊乙肝伴黄疸的治疗效果.方法 将2015年8月~2016年12月于本院接受诊断并初诊为乙肝伴黄疸的88例患者,根据治疗方式的不同,随机分为对照组和治疗组,各44例.对照组进行护肝降酶、抗病毒等常规治疗,治疗组在对照组基础上给予清热疏肝退黄汤剂治疗,比较2组患者治疗前后肝功能指标变化、胆红素变化、临床证候变化及治疗效果等. 结果 2组血清总胆红素(TBIL)、结合胆红素(DBIL)、谷丙转氨酶(ALT)和凝血酶原时间(PT)均显著降低(P<0.05),白蛋白显著升高(P<0.05),且治疗后治疗组TBIL、DBIL、ALT与白蛋白变化幅度显著高于对照组,差异具有统计学意义(P<0.05);2组乙肝病毒DNA拷贝量均下降(P<0.05),且治疗组显著低于对照组,差异具有统计学意义(P<0.05);2组身目发黄、脘闷腹胀、胁肋疼痛、食欲不振、困倦乏力症状积分均显著下降(P<0.05),且治疗组下降幅度显著高于对照组,差异具有统计学意义(P<0.05);治疗组总有效率97.73%,而对照组则为81.82%,2组差异具有统计学意义(P<0.05).结论 清热疏肝退黄汤治疗乙肝伴黄疸患者,可显著改善黄疸症状,改善肝功能损伤,效果显著,具有重要临床应用价值.
Clinical observation of qingre shugan tuihuang tang in the treatment of newly diagnosed hepatitis B with jaundice
Objective To study treatment effect of qingre shugan tuihuang tang in the treatment of newly diagnosed hepatitis B with jaundice.Methods88 patients newly diagnosed hepatitis B with jaundice in our hospital from August 2015 to December 2016 were randomly divided into control group and treatment group according to different modes of treatment, control group was given protecting liver and reducing enzyme, antivirus and other conventional therapy, treatment group added qingre shugan tuihuang tang on the basis of control group, changes of liver function indexes, changes of bilirubin, changes of clinical syndromes and treatment effect in the two groups were compared.ResultsSerum total bilirubin (TBIL), direct bilirubin (DBIL), Alanine transaminase (ALT) and prothrombin time (PT) in the two groups were significantly decreased (P<0.05), albumin was significantly increased (P<0.05), and rangeability of TBIL, DBIL, ALT and albumin in treatment group after the treatment were significantly higher than control group, the difference was statistically significant (P<0.05);hepatitis B virus DNA copy numbers in the two groups were significantly decreased (P<0.05), treatment group was significantly lower than control group, the difference was statistically significant (P<0.05);yellow tint of sclera and skin, gastric distention, rib-side pain, anorexia, drowsiness and fatigue symptom scores in the two groups were significantly decreased (P<0.05), decrease of treatment group was significantly higher than control group, the difference was statistically significant (P<0.05);total effective rate of treatment group was 97.73%, while the control group was 81.82%, the two groups had significant difference (P<0.05).ConclusionQingre shugan tuihuang tang in the treatment of newly diagnosed hepatitis B with jaundice can improve symptoms of jaundice significantly, improve liver function injury, effect is remarkable, its clinical application is very important.

Qingre shugan tuihuang tangchronic hepatitis Bjaundicenewly diagnosed

郭晓军、刘源远、张玲、张长江

展开 >

海军青岛第二疗养院 干部二科,山东 青岛 266000

海军青岛第二疗养院 特勤一科,山东 青岛 266000

第二军医大学附属长海医院 消化内科,上海 200433

第三军医大学附属西南医院 传染病专科医院 重庆 400038

展开 >

清热疏肝退黄汤 慢性乙型肝炎 黄疸 初诊

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
  • 3
  • 9