首页|复方丹参注射液治疗急性病毒性心肌炎的疗效观察

复方丹参注射液治疗急性病毒性心肌炎的疗效观察

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目的 观察复方丹参注射液治疗急性病毒性心肌炎的疗效.方法 2015年5月~2017年2月余杭区第二人民医院内一科收治的128例急性病毒性心肌炎患者进行随机分组,各64例.2组均接受常规治疗方案,观察组另给予复方丹参注射液,评价复方丹参注射液对该疾病的效果.结果 ①观察组总有效率为93.75%,高于对照组76.56%(P<0.05).②经治疗,观察组血清TNF-ɑ和IL-6水平分别为[(72.4±10.4)、(36.15±4.68)]ng/L,均低于对照组[(95.0±12.7)、(46.23±5.24)]ng/L(P<0.05).③经治疗,观察组血清AST、CK-MB和LDHI水平分别为[(43.19±3.25)、(17.34±3.31)、(168.4±13.9)]U/L,均低于对照组[(52.09±4.61)、(25.55±3.86)、(201.5±15.4)U/L](P<0.05).④对照组未出现明显不良反应,观察组出现3.13%的不良反应,2组比较差异无统计学意义.结论 复方丹参注射液可降低急性病毒性心肌炎患者炎症水平,保护患者心肌细胞,提高治疗效果.
Effects of Compound Danshen injection on acute viral myocarditis
Objective To analyse effects of Compound Danshen injection on acute viral myocarditis.Methods-128 patients with acute viral myocarditis were divided into two groups from May 2015 to February 2017 in Yuhang District, the Second People's Hospital.The two groups received the conventional treatment plan, the observation group was given compound Danshen injection, the evaluation of compound Danshen injection on the disease effect.Results①Total efficiency of observation group was 93.75%,higher than that of control group 76.56%(P<0.05).②Serum TNF-ɑ and IL-6 level of observation group were[(72.4±10.4), (36.15±4.68)]ng/L,lower than that of control group[(95.0±12.7), (46.23±5.24)ng/L](P<0.05).③Serum AST,CK-MB and LDHI level of observation group were[(43.19±3.25), (17.34±3.31), (168.4±13.9)]U/L,lower than that of control group[(0.47±0.08)μg/L, (9.05±1.93)mg/L)](P<0.05).Whole blood viscosity,plasma viscosity and FIB level of observation group were[(5.95±1.91)mPa·s, (1.49±0.17)mPa·s, (3.20±0.58g/L)],lower than that of control group[(52.09±4.61), (25.55±3.86),(201.5±15.4)U/L](P<0.05).④There was no obvious adverse reaction in the control group and the observation group had 3.13% adverse reactions.ConclusionCompound Danshen injection can reduce the level of inflammation in patients with acute viral myocarditis,protect myocardial cells and improve treatment effect.

Compound Danshen injectionacute viral myocarditisinflammationmyocardial enzyme

马荣国、罗培

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余杭区第二人民医院 内一科,浙江 杭州 311121

复方丹参注射液 急性病毒性心肌炎 炎症 心肌酶

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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