首页|齐拉西酮治疗首发精神分裂症78例临床研究

齐拉西酮治疗首发精神分裂症78例临床研究

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目的 探讨首发精神分裂症患者接受齐拉西酮治疗的临床疗效.方法 选择2014年1月~2016年6月在浙江省舟山市第二人民医院精神科接受治疗的首发精神分裂症患者156例为研究对象,将其随机均分为2组,对照组采用利培酮进行治疗,观察组选用齐拉西酮进行治疗,对比2组患者的治疗后的临床疗效. 结果 观察组患者治疗的总有效率为97.4%,对照组患者治疗的总有效率为89.7%;观察组患者治疗后的阴性症状评分明显低于对照组,2组对比具有统计学意义(P<0.05).结论 齐拉西酮应用于首发精神分裂症的治疗取得了良好的临床疗效,治疗的总有效率较高,有效控制了阴性症状.
Clinical study of ziprasidone in the treatment of 78 patients with first-episode schizophrenia
Objective To investigate the clinical efficacy of ziprasidone in the treatment of first-episode schizophrenia.Methodsfrom January 2014 to June 2016to receive the treatment of patients with first-episode schizophrenia in 156 cases as the research object in the psychiatric hospital, which were randomly divided into two groups, the control group were given risperidone treatment, the observation group was treated with ziprasidone treatment, compared two groups of clinical curative effect of the treatment of patients after.ResultsThe patients in the observation group the total effective rate was 97.4%, the control group total effective rate was 89.7%;group after treatment in patients with negative symptoms score were significantly lower than the control group, with statistical significance between the two groups (P<0.05).ConclusionThe application of ziprasidone in the treatment of first-episode schizophrenia has achieved good clinical efficacy, the total effective rate of treatment is higher, and the negative symptoms are effectively controlled.

first-episode schizophreniarisperidoneziprasidoneclinical efficacy

庄妙红、王建林、武勇法、乐军儿、林彩霞、徐燕

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浙江省舟山市第二人民医院 公共卫生科,浙江 舟山 316000

浙江省舟山市第二人民医院 精神科女病区, 浙江 舟山 316000

浙江省舟山市第二人民医院 精神科男病区,浙江 舟山 316000

浙江省舟山市第二人民医院 心身科,浙江 舟山 316000

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首发精神分裂症 利培酮 齐拉西酮 临床疗效

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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