首页|异丙酚与依托咪酯在小儿手术麻醉中诱导效果及苏醒比较

异丙酚与依托咪酯在小儿手术麻醉中诱导效果及苏醒比较

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目的 探析异丙酚与依托咪酯在小儿手术麻醉中诱导效果及苏醒情况.方法 前瞻性选取西宁市第三人民医院儿科2013年5月~2015年1月收治的120例小儿手术患者作为研究对象,采用随机数字表法将其分为2组,分别为对照组和观察组,每组60例.对照组麻醉诱导采用依托咪酯,观察组麻醉诱导采用异丙酚,观察2组患儿麻醉效果、苏醒情况及在麻醉诱导期中的不良反应.结果 观察组患儿麻醉满意度评分明显高于对照组(P<0.05);且观察组清醒时间和离室时间均明显短于对照组(P<0.05);观察组呼吸抑制、躁动、喉及支气管痉挛、恶心呕吐等不良反应均明显低于对照组(P<0.05).结论 异丙酚比依托咪酯更适合应用于小儿手术麻醉,且麻醉效果显著,苏醒快,值得临床应用与推广.
Induction and recovery of propofol and etomidate in pediatric anesthesia
Objective To explore the effect of propofol and etomidate on anesthesia induction in pediatric surgery, and to provide evidence for the future use of anesthesia in pediatric surgery.Methods120 cases of pediatric surgery patients were prospectively selected pediatric in our hospital from May 2013 to January 2015 as the research object, randomly divided into 2 group respectively, control group and observation group, 60 cases in each group;the control group anesthesia was induced with etomidate, observation group anesthesia was induced with propofol, and the anesthetic effect were observed in the two groups, recovery and adverse reaction in the induction period of anesthesia.ResultsThe patients in the observation group anesthesia satisfaction scores were significantly higher than the control group (P<0.05) and the observation group;the recovery time and the time of leaving room were significantly shorter than the control group (P<0.05);in the observation group, respiratory depression, restlessness, throat and bronchial spasm, adverse reactions such as nausea and vomiting were significantly lower than the control group (P<0.05).ConclusionPropofol is more suitable for pediatric surgery than etomidate, and anesthesia effect is remarkable, fast recovery, worthy of clinical application and promotion.

propofoletomidateinductionrecovery

姜勇、唐晓慧、侯得伟

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西宁市第三人民医院 儿科,青海 西宁 810005

异丙酚 依托咪酯 诱导 苏醒

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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