摘要
目的 探讨阿奇霉素联合特布他林对小儿肺炎的治疗效果及对症状改善的影响.方法 回顾性分析2014年1月~2016年12月在台州市中西医结合医院儿科接受治疗的肺炎患儿的临床资料,根据其治疗方式分为对照组和观察组,对照组给予阿奇霉素治疗,观察组在此基础上给予特布他林雾化治疗.观察2组患儿的治疗效果,比较2组患儿治疗前后临床症状积分、炎症因子水平差异.结果 观察组治疗的有效率为98.00%,明显高于对照组84.00%;2组患儿治疗前临床症状积分差异无统计学意义,治疗后,观察组咳嗽、咳痰、发热和啰音得分低于对照组;2组患儿治疗前炎症因子水平差异无统计学意义,治疗后,观察组IL-6、IL-8、TNF-α和CRP水平低于对照组.结论 阿奇霉素联合特布他林对小儿肺炎有较好的治疗效果,可明显改善临床症状,降低炎症因子水平,具有较好的临床应用价值.
Abstract
Objective To investigate the effect of Azithromycin combined with terbutaline on the treatment of pneumonia in children and its effect on symptom improvement.MethodsThe clinical data of children with pneumonia treated in Taizhou Hospital of traditional Chinese and Western medicine from January 2014 to December 2016 were retrospectively analyzed, according to the treatment methods,the patients were divided into control group and observation group, the control group was given azithromycin treatment, the observation group on this basis to give terbutaline atomization treatment.The therapeutic effects of the two groups were observed, and the differences of clinical symptom score, inflammatory factor level were compared between the two groups before and after treatment.ResultsThe effective rate of the observation group was 98%, which was significantly higher than that of the control group (84%);The clinical symptom score had no difference between the two groups before treatment, after treatment, the observation group of cough, expectoration, fever and rales were lower than those in the control group;The two groups had no difference between the levels of proinflammatory cytokines, after treatment, the observation group IL-6, IL-8, TNF-and CRP levels were lower than the control group.ConclusionAzithromycin combined with terbutaline in the treatment of children with pneumonia has a better therapeutic effect, can significantly improve the clinical symptoms, reduce the level of inflammatory factors, has a good clinical value.
NETL
NSTL
维普
万方数据