首页|小儿区域麻醉中应用氯胺酮和芬太尼的差异研究

小儿区域麻醉中应用氯胺酮和芬太尼的差异研究

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目的 探究小儿区域麻醉中应用氯胺酮和芬太尼的差异性与临床效果.方法 回顾性分析2014年6月~2015年12月隆德县人民医院接受治疗的60例手术患儿的临床资料,随机分为2组,每组30例.对照组给予单纯的氯胺酮麻醉;干预组给予氯胺酮与芬太尼联合麻醉,对2组患儿麻醉后的心率、呼吸、动脉压等指标以及麻醉效果进行综合评价.结果 干预组患儿麻醉后的心率、呼吸频率、平均动脉圧以及脉搏氧饱和度明显优于对照组,差异有统计学意义(P<0.05);且干预组的唤醒时间、氯胺酮用量以及氯胺酮追加次数显著低于对照组,差异有统计学意义(P<0.05).结论 对行区域阻滞的手术患儿给予氯胺酮和芬太尼联合辅助麻醉,能够稳定患儿的心率、呼吸频率等,缩短术后唤醒时间,减少麻醉药物的使用量,具有较高的安全性,麻醉效果显著,可以在临床中得以广泛地推广应用.
Study on the differences of Ketamine and Fentanyl in pediatric regional anesthesia
Objective To explore the difference and clinical effect in pediatric regional anesthesia with ketamine and fentanyl.MethodsThe clinical data of 60 cases of children with surgical treatment from June 2014 to December 2015 in Longde People's Hospital were retrospectively analyzed and randomly divided into two groups,with 30 cases in each group.The control group was given simple ketamine anesthesia;The intervention group was given ketamine combined with fentanyl anesthesia, of children with breathing,After anesthesia,the heart rate, respiratory,arterial pressure and other indicators and the anesthetic effect of the two groups were comprehensively evaluated.ResultsIn the intervention group after anesthesia, heart rate, respiratory rate, mean arterial pressure and pulse oxygen saturation was significantly better than the control group, there was statistical significance (P<0.05);and wake-up time in the intervention group, the dosage of ketamine and ketamine bolus times was significantly lower than the control group,there was statistical significance (P<0.05).ConclusionThe regional anesthesia operation were given ketamine and fentanyl assisted anesthesia, can stabilize children's heart rate, respiratory rate, shorten postoperative awake time, reduce anesthetic dosage, higher safety, anesthetic effect, can be widely applied in clinical.

pediatric regional anesthesiaketaminefentanylclinical efficacy

沈晓芸

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隆德县人民医院 麻醉科,宁夏 隆德 756300

小儿区域麻醉 氯胺酮 芬太尼 临床疗效

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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