首页|布地奈德吸入联合心理干预治疗慢性阻塞性肺疾病的效果研究

布地奈德吸入联合心理干预治疗慢性阻塞性肺疾病的效果研究

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目的 探究分析布地奈德吸入联合心理干预治疗慢性阻塞性肺疾病的临床效果,总结临床医学施治经验.方法 选取浙江省诸暨市中心医院自2012年7月~2017年4月间接收治疗的慢性阻塞性肺疾患者者80例作为研究对象,将上述患者的相关临床资料收集好之后,随机将所有患者均分成治疗组和对照组2组,每组40例,医生对研究组患者采用布地奈德吸入联合心理干预进行治疗,对照组患者单纯采用布地奈德吸入治疗,观察2组血清重塑指标变化、血气指标变化和痰液粘性指标变化,统计临床疗效.结果 治疗后,研究组血清碱性咸纤维细胞生长因子(serum basic fibroblast growth factor,b-FGF)、神经生长因子(nerve growth factor,NGF)和金属蛋白酶组织抑制剂-1(Tissue inhibitor of metalloproteinase-1,TIMP-1)、痰液白细胞介素-8(Sputum interleukin LL-8)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)以及PaO2、PaCO2等方面的统计指标明显好于对照组;研究组患者治疗效果远好于对照组患者.结论 布地奈德吸入联合心理干预治疗慢性阻塞性肺疾病的治疗效果较常规治疗效果更为显著.
Effect of budesonide inhalation combined with psychological intervention on chronic obstructive pulmonary disease
Objective To explore the clinical effect of budesonide inhalation combined with psychological intervention in the treatment of chronic obstructive pulmonary disease (COPD).MethodsSelected in Zhuji city center hospital from July 2012 to April 2017 year to receive treatment in patients with chronic obstructive pulmonary disease in 80 cases as the research object, after the patient related clinical data, all patients were randomly divided into treatment group and control group two groups, each group of 40 cases of patients in the study group of patients with a doctor inhaled budesonide combined with psychological intervention treatment, inhalation therapy on the comparison group of patients treated with budesonide, observe the changes of two groups, serum blood gas index change and remodeling index sputum viscous indicators clinical statistics.ResultsAfter treatment the corresponding treatment after the intervention, the study group of serum basic fibroblast growth factor Xian (b-FGF), nerve growth factor (NGF) and tissue inhibitor of metalloproteinase-1 (TIMP-1), sputum interleukin-8, tumor necrosis factor alpha and PaO2, PaCO2 and other aspects of the statistical index is obviously better than the contrast group;the study group of patients treatment effect is much higher than that of contrast group patients.ConclusionBudesonide inhalation combined with psychological intervention in the treatment of chronic obstructive pulmonary disease is more effective than conventional treatment, which is worthy of popularization and application in clinical medicine.

budesonidepsychological interventionchronic obstructive pulmonary disease

杨玉萍、俞永江

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浙江省诸暨市中心医院 全科,浙江 诸暨 311800

布地奈德 心理干预治疗 慢性阻塞性肺疾病

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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