中国生化药物杂志2017,Vol.37Issue(6) :339-341.DOI:10.3969/j.issn.1005-1678.2017.06.129

关节腔注射玻璃酸钠联合心理干预治疗膝关节骨性关节炎疗效观察

Observation of the effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis

李云 尹会 阮文东
中国生化药物杂志2017,Vol.37Issue(6) :339-341.DOI:10.3969/j.issn.1005-1678.2017.06.129

关节腔注射玻璃酸钠联合心理干预治疗膝关节骨性关节炎疗效观察

Observation of the effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis

李云 1尹会 2阮文东2
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作者信息

  • 1. 天津医科大学总医院 药剂科,天津 300052
  • 2. 天津医科大学总医院 骨科,天津 300052
  • 折叠

摘要

目的 探讨关节腔注射玻璃酸钠联合心理干预治疗膝关节骨性关节炎患者的临床效果.方法 选取2015年6月~2016年6月天津医科大学总医院诊治的90例膝关节骨性关节炎患者作为研究对象,根据治疗方式不同分为2组,每组45例.对照组患者采用常规方式治疗,观察组患者用常规方式+关节腔注射玻璃酸钠治疗;比较2组患者各项实验数据.结果 观察组患者治疗后膝关节疼痛评分、关节积液量与关节活动度变化情况优于对照组;观察组患者治疗后膝关节功能评分变化情况优于对照组;观察组临床治疗效果(95.6%)优于对照组(75.6%).组间比较差异均有统计学意义(P<0.05);2组患者接受治疗中均未出现严重不良反应,组间比较差异无统计学意义.结论 用常规方式+关节腔注射玻璃酸钠治疗膝关节骨性关节炎患者临床效果佳,值得临床上广泛应用.

Abstract

Objective To investigate the clinical effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis.MethodsA total of 90 patients with knee osteoarthritis treated in our hospital from June 2015 to June 2016 were selected as the research object, according to the different treatment methods, the patients were divided into two groups,with 45 cases in each group.The patients in the control group were treated with conventional treatment, while the observation group was treated with conventional therapy and intra-articular injection of sodium hyaluronate.The experimental data of the two groups were compared.ResultsAfter treatment, the changes of knee joint pain score, joint effusion and joint mobility in the observation group is better than those in the control group.The change of knee function score in the observation group was better than that in the control group.The clinical therapeutic effect of the observation group (95.6%) is better than that of the control group (75.6%);There was significant difference between the two groups (P<0.05);There were no serious adverse reactions in the two groups of patients receiving treatment,and there was no significant difference between the two groups.ConclusionThe clinical effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis is good, which is worthy of clinical application.

关键词

膝关节/骨性关节炎/关节腔/玻璃酸钠

Key words

knee joint/osteoarthritis/articular cavity/sodium hyaluronate

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量3
参考文献量8
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