目的 研究分析他汀类药物在状动脉粥样硬化性心脏病(冠心病)整体防治中的临床意义方法.方法 选取2013年12月~2014年11月在湖州市第一人民医院治疗的167例冠心病患者作为研究对象,根据患者的实际病情对患者采用不同的他汀类药物如阿托伐他汀、瑞舒伐他汀、辛伐他汀等药物治疗,比较治疗前后的总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、高密度脂蛋白(high density lipoprotein,HDL)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)水平.结果 167例患者治疗3个月后的TC、TG、HDL 、LDL-C、HDL-C值显著优于治疗前,差异有统计学意义(P<0.05);患者治疗后3、6、12个月的指标值有所改善,但比较差异无统计学意义.结论 采用他汀类药物治疗冠心病疗效显著,可较好地改善临床指标.
The important role of statins in the prevention and treatment of coronary heart disease
Objective To study the importance of statins in the prevention and treatment of coronary heart disease.Methods167 cases of coronary heart disease in our hospital from December 2013 to November 2014 were chosen as the research object, patients were given different statins such as atorvastatin, rosuvastatin and simvastatin treatment, and total cholesterol(TC),triglyceride(TG), low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol (HDL-C)before and after treatment were statistically analyzed.Results3 months after treatment TC,TG,LDL-C,HDL-C were significantly better than before treatment(P< 0.05);3 months after treatment, 6 months and 12 months, the index value has improved, but the differencehad no statistical significance.ConclusionThe use of statins in coronary heart disease has a significant effect,can improve the clinical indicators.
NETL
NSTL
万方数据
维普
