首页|口服盐酸氨基葡萄糖胶囊配合关节腔内注射玻璃酸钠结合功能锻炼治疗膝骨关节炎的临床研究

口服盐酸氨基葡萄糖胶囊配合关节腔内注射玻璃酸钠结合功能锻炼治疗膝骨关节炎的临床研究

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目的 探讨口服盐酸氨基葡萄糖胶囊配合关节腔内注射玻璃酸钠结合功能锻炼的三联疗法治疗膝骨关节炎是否有更加良好的临床效果.方法 选取本院进行治疗的膝骨关节炎患者120例,随机将他们分为2组,研究组进行口服盐酸氨基葡萄糖胶囊联合关节腔内注射玻璃酸钠配合功能锻炼治疗的三联疗法,而对照组只口服盐酸氨基葡萄糖胶囊,分析2组患者的临床效果,确定是否有显著差异.结果 2组患者经过治疗后研究组的VAS评分、血清炎性分子水平及Lequesne指数的研究结果显示,其效果都显著优于对照组(P<0.05).结论 口服盐酸氨基葡萄糖胶囊联合关节腔内注射玻璃酸钠配合功能锻炼的三联治疗对膝骨关节炎效果显著,在提高患者生活质量方面更加有利.
Clinical study on treating of the knee osteoarthritis by using glucosamine capsule and injecting sodium hyaluronate combined with appropriate functional exercise
Objective To investigate the clinical effect of three capsule combined with Function injection combined with functional exercise in the treatment of knee osteoarthritis.Methods120 patients with knee osteoarthritis were randomly divided into two groups, the study group took orally hydrochloride capsule combined with joints injection combined with functional exercise therapy, and the control group only oral glucose capsules.two groups of patients after a period of treatment.ResultsIn the VAS score, lequesne index and serum inflammatory molecular level of the two groups were significantly better than the control group (P<0.05).ConclusionWhich the clinical study on treating of the knee osteoarthritis by using glucosamine capsule and injecting sodium hyaluronate combined with appropriate functional exercise has a significant effect on knee osteoarthritis, and more favorable in improving the quality of life of patients.

osteoarthritis(OA)hydrochloride glucosamine capsulesodium hyaluronatefunctional exercise

毛立新、吴发荣

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常山县人民医院 药剂科,浙江 衢州 324200

常山县人民医院 康复科,浙江 衢州 324200

膝骨关节炎 盐酸氨基葡萄糖胶囊 玻璃酸钠 功能锻炼

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(6)
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