摘要
目的 研究少弱精症患者血液微量元素与精液质量的相关性,以期指导临床治疗.方法 选取2015年3月~2016年10月间入院诊治的少精弱精症患者78例作为观察组,同时选取同期入院体检的健康男性42例作为对照组.2组男性均行常规精液分析与血液微量元素的含量检测.结果 观察组血清钙与铜的含量与对照组差异并不显著;而观察组血清含锌量为(7.23±2.70)μmol/L、含铅量为(29.33±15.97)μg/L,对照组则分别为(13.37±2.34)μmol/L、含铅量为(7.09±5.74)μg/L;2组差异显著(P<0.05).观察组血清锌含量与精子活率负相关(r=-0.162,P<0.05),含铅量与精子密度、正常形态精子率、精子活率均负相关(r分别为-0.112、-0.067、-0.142,P<0.05),含铜量与精子密度正相关而与前向运动精子率负相关(r分别为0.058、-0.137,P<0.05).结论 少弱精症患者血液锌、铅、铜的含量与精液质量密切相关,严密监测可指导临床治疗.
Abstract
Objective To study less weak blood trace elements and semen quality in patients with azoospermia relevance to guide the clinical treatment.MethodsMarch 2015 to October 2016 and less refined asthenospermia diagnosis and treatment of 78 cases of patients admitted to hospital as the observation group, while admission examination to select healthy men the same period 42 cases as the control group.Two men underwent routine semen analysis and content detection of trace elements in the blood.ResultsThe difference between serum calcium and copper content in the control group was not significant;and serum zinc content of the observation group (7.23±2.70)μmol/L, lead content was (29.33±15.97)μg/L, the control group respectively (13.37±2.34)μmol/L, lead content was (7.09±5.74)μg/L;the difference was significant (P<0.05).Observed a negative correlation of serum zinc content and sperm motility (r=-0.162, P<0.05), the lead content and sperm density, normal sperm morphology rate, sperm motility rate negative correlation (r=-0.112,-0.067,-0.142, P<0.05), the copper content and sperm density positively correlated with the forward movement of sperm rate negatively correlated (r=0.058,-0.137, P<0.05).ConclusionWeak content less closely related to the quality of semen azoospermia patient's blood zinc, lead, copper, and close monitoring to guide clinical treatment.
NETL
NSTL
维普
万方数据