高敏肌钙蛋白T与急性ST段抬高型心肌梗死介入术后冠状血流状态相关性研究
Study on the association of hypersensitivity troponin T level with coronary flow in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
刘梦平 1刘宝奇2
作者信息
- 1. 西安交通大学第一附属医院 心内科,陕西 西安 710061
- 2. 榆林市府谷县人民医院 心内科,陕西 榆林 719400
- 折叠
摘要
目的 研究住院期间高敏性肌钙蛋白T与急性ST段抬高型心肌梗死(STEMI)患者经PCI术后冠状脉血流的相关性.方法 选取2014年1月~2016年12月期间就诊于本院的130例急性STEMI患者,根据高敏性肌钙蛋白T含量,将STEMI患者分为阳性组和阴性组.多变量分析住院期间高敏性肌钙蛋白T含量与STEMI患者PCI术后冠脉血流相关性.结果 阳性组无复流发生率显著高于阴性组(P<0.05),左心室射血分数显著低于阴性组(P<0.05).多变量分析表明,高敏性肌钙蛋白T与急性STEMI患者PCI术后冠状血流无复流、TIMI血流分级事件独立相关(P<0.05).结论 高敏性肌钙蛋白T是预测STEMI患者PCI术后冠脉血流受损和评估STEMI患者危险分层有效标志物.
Abstract
Objective To study the the association of Hs-cTNT level with coronary flow in patients with ST-segment elevation myocardial infarction(STEMI) undergoing percutaneous coronary intervention(PCI).Methods130 cases with STEMI in hospital from January 2014 to December 2014 were divided into the positive group and the negative group according the level of Hs-cTNT.Multivariate analysis were used to examine the association of Hs-cTNT with coronary flow in patients with ST-Segment elevation myocardial infarction undergoing primary PCI.ResultsThe incidence of no reflow in the positive group was significantly higher than that in the negative group (P<0.05) The left ventricular ejection fraction in the positive group was significantly lower than that in the negative group (P<0.05).Multivariate analysis showed that Hs-cTNT was independently associated with coronary flow no-reflow in patients with acute STEMI post-PCI and TIMI flow fractionation events(P<0.05).ConclusionHypersensitivity troponin T is an effective marker for predicting coronary artery flow damage in patients with STEMI after PCI and evaluating risk stratification in patients with STEMI.
关键词
高敏肌钙蛋白T/ST段抬高型心肌梗死/紧急经皮冠状动脉介入术/冠状动脉血流Key words
Hypersensitivity troponin T/ST-segment elevation myocardial infarction/primary percutaneous coronary intervention/coronary blood flow引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据