首页|中药活血化瘀法对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响

中药活血化瘀法对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响

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目的 研究灯盏花素针对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响.方法 选取本院100例低灌注/栓子清除能力减小型脑梗死病例作为研究对象,随机均分为2组,对照组使用常规西药,实验组加用灯盏花素针,比较2组血浆D二聚体(D-D)、纤维蛋白原(Fib)、收缩压、舒张压、神经功能恢复效果.结果 实验组D-D、Fib水平、NIHSS评分均明显小于对照组(P<0.05),且收缩压明显高于对照组(P<0.05).结论 灯盏花素针可降低低灌注/栓子清除能力减小型脑梗死患者血浆D-D与Fib浓度,增加脑血流灌注量,有效改善神经功能损伤情况.
Effect of TCM for removing blood stasis on promoting blood circulation and cerebral blood perfusion in patients with hypoperfusion/decreased embolic clearance type cerebral infarction
Objective To study the effect of breviscapine injection on cerebral blood perfusion in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.Methods 100 patients with hypoperfusion/decreased embolic clearance type cerebral infarction in our hospital were selected and randomly divided into two groups.Both group were treated with conventional western medicines, and the experimental group was additionally treated with breviscapine injection.The plasma D-dimer (D-D), fibrinogen (Fib), systolic and diastolic blood pressure and recovery of neurological function were compared between the two groups.Results D-D and Fib levels and NIHSS score in the experimental group were significantly lower than those in the control group (P< 0.05), while the systolic blood pressure was significantly higher than that in the control group (P< 0.05).Conclusion Breviscapine injection can reduce the plasma D-D and Fib levels, increase cerebral vascular blood flow and improve the neurological function in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.

method for promoting blood circulation and removing blood stasishypoperfusioncerebral infarctioncerebral blood perfusion

郑高、周杨、沈志华

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绍兴市中心医院 神经内科,浙江 绍兴 312030

绍兴市中心医院 临床药学室,浙江 绍兴 312030

活血化瘀法 低灌注 脑梗死 脑血流灌注量

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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