首页|水针刀结合通痹酊剂加热敷对膝骨关节病的血沉、CRP、IL-1的影响

水针刀结合通痹酊剂加热敷对膝骨关节病的血沉、CRP、IL-1的影响

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目的 观察水针刀结合通痹酊剂加热敷对膝骨关节病的血沉、CRP、IL-1的因素的影响.方法 96例膝骨关节病患者按治疗方式均分为对照组与实验组(n=48),对照组选用水针刀治疗,实验组在水针刀基础上结合通痹剂加热敷治疗,均持续治疗14天.观察2组临床疗效,CRP、IL-1、血沉、膝关节功能损伤评分及安全性.结果 实验组总有效率93.75%高于对照组79.17%(P<0.05).治疗后,实验组CRP、IL-1、血沉低于对照组[(7.09±0.97)mg/L、(6.54±0.82)ng/L、(16.47±2.03)mm/h 比(10.35±1.28)mg/L、(7.21±0.93)ng/L、(18.25±2.21)mm/h](P<0.05).实验组膝关节功能损伤评分较对照组高(P<0.05).2组安全性比较差异无统计学意义.结论 水针刀结合通痹剂加热敷治疗膝骨关节病的临床疗效优于水针刀,能够促进炎症的吸收,缓解膝关节功能.
Effects of injection needle scalpel combined with Tongbi tincture hot compress on the erythrocyte sedimentation rate, CRP and IL-1 in knee osteoarthritis
Objective To observe the effect of injection needle scalpel combined with Tongbi tincture heat deposited on the erythrocyte sedimentation rate, CRP and IL-1 in knee osteoarthritis.Methods 96 cases of knee osteoarthrosis according to the treatment divided into the control group(n=48) and experimental group(n=48), the control group was treated with injection needle scalpel, the experimental group on the basis of injection needle scalpel combination of tongbi tincture heat deposited, all lasted for 14 days.The clinical efficacy, CRP, IL-1, blood sink, knee joint functional impairment score, and safety was observed in the two groups.Results The total effective rate of the experimental group was 93.75%,higher than the control group 79.17%(P<0.05).After treatment, the CRP, IL-1, blood sedimentation of experimental group was lower than the control group[(7.09±0.97)mg/L,(6.54±0.82) ng/L,(16.47±2.03) mm/h vs.(10.35±1.28) mg/L,(7.21±0.93) ng/L,(18.25±2.21) mm/h](P<0.05).The scores of knee joint function impairment in the experimental group was higher than that in the control group(P<0.05).There was no significant difference in safety between the two groups.Conclusion The therapeutic effect of injection needle scalpel combined with Tongbi tincture heat deposited in treatment knee osteoarthrosis is better than injection needle scalpel.It can promote the absorption of inflammation, relieve knee function.

knee osteoarthrosisinjection needle scalpeltongbi tincture heat depositedclinical curative effect

张里援、吴惠明

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温州市中医院 骨伤科,浙江 温州 325000

膝骨关节病 水针刀 通痹酊剂加热敷 临床疗效

温州市公益性社会发展医疗卫生科技项目

Y20160383

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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