首页|复方丹参滴丸联合低频脉冲电刺激在脑卒中后康复期中的应用

复方丹参滴丸联合低频脉冲电刺激在脑卒中后康复期中的应用

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目的 观察复方丹参滴丸联合低频脉冲电刺激在脑卒中后康复期中的应用效果.方法 将90例脑卒中康复期患者随机分为对照组和观察组,每组45例;对照组给予低频脉冲电刺激治疗,观察组同时口服复方丹参滴丸;分别于治疗前后检测患者血沉(ESR)、颈内动脉颅外段血流速度(ICAex)、周围组织微循环血流灌注量(PU)水平,行神经功能缺损程度、Fugl-Meyer上肢部分(FMA-UE)、运动功能状态量表(MSS)及改良Barther指数(MBI)评分.结果 治疗后,观察组较对照组ESR明显减小(P<0.05),ICAex、PU明显增大(P<0.05);治疗后,观察组较对照组神经功能缺损评分明显降低(P<0.05),FMA-UE、MSS、MBI评分均明显升高(P<0.05).结论 复方丹参滴丸联合低频脉冲电刺激为脑卒中后康复期有效治疗手段,可有效改善颅内血流灌注,减轻神经功能损伤,促进肢体功能恢复.
Application of compound Danshen Dripping pill combined with lowfrequency pulsed electrical stimulation in post-stroke rehabilitation
Objective To observe the effects of compound Danshen dropping pill combined with low frequency pulsed electrical stimulation in rehabilitation period after stroke.Methods 90 stroke patients in recovery period were randomly divided into control group and observation group with 45 cases in each group.The control group was treated with low frequency pulsed electrical stimulation while the observation group was additionally given oral compound Danshen dripping pill.The levels of erythrocyte sedimentation rate(ESR), extracranial internal carotid artery blood flow velocity(ICAex), microcirculation blood flow perfusion(PU), and the scores of neurological deficit, Fugl-Meyer upper limb fraction(FMA-UE), the motion function status Scale(MSS) and the improved Barther Index(MBI) were measured before and after treatment.Results After treatment, the ESR of the observation group was significantly lower than that of the control group(P<0.05), and ICAex and PU were significantly increased(P<0.05).The score of neurological deficit in the observation group was significantly lower than that in the control group(P<0.05), and the scores of FMA-MS, MSS and MBI were significantly increased(P<0.05).Conclusion Compound Danshen Dripping Pill combined with low frequency pulse electrical stimulation is an effective treatment after stroke, and can effectively improve intracranial blood perfusion, reduce neurological damage and promote limb function recovery.

strokerehabilitation periodcompound Danshen dripping pill

张竞超、诸葛爱梅

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天津市第五中心医院 药剂科,天津 300450

脑卒中 康复期 复方丹参滴丸

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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