首页|加减毓麟汤对卵巢早衰患者生殖内分泌相关指标及卵巢功能的影响

加减毓麟汤对卵巢早衰患者生殖内分泌相关指标及卵巢功能的影响

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目的 分析加减毓麟汤辅助治疗卵巢早衰患者的激素及卵巢功能的影响.方法 选择我院诊断为卵巢早衰且表现为肾阳虚证的142例患者为研究对象,采用随机数字表法分为对照组(64例)与观察组(78例),观察2组患者治疗前后的血清激素水平、卵巢功能及中医症候积分.结果 治疗前2组患者各项评分及激素水平无显著差异,治疗后2组血清FSH、LH、E2均显著下降,且观察组变化幅度均显著高于对照组(P<0.05);2组中医症候积分较治疗前均显著下降,且观察组显著低于对照组(P<0.05).结论 加减毓麟汤对卵巢早衰脾肾阳虚症患者治疗疗效显著,可显著改善患者雌激素水平,调整内分泌,改善临床症状,效果显著.
Effect of modified Yulin Decoction on reproductive endocrine related indexes and ovarian function in patients with premature ovarian failure
Objective To analyze the effect of modified Yulin Decoction on hormones and ovarian function in patients with premature ovarian failure (POF).Methods 142 cases of patients with POF and kidney-yang deficiency syndrome were selected and randomLy divided into the control group (n=64) and the observation group (n=78).Levels of serum hormones and ovarian function,the traditional Chinese medicine (TCM) symptom score in the two groups were observed before and after treatment.Results Before treatment, there were no significant differences between the two groups in the scores and levels of hormones.After treatment, levels of serum FSH, LH and E2 were significantly decreased in the two groups, and the changes were more obvious in the observation group than the control group (P<0.05).After treatment, TCM symptom scores of two groups were significantly decreased, and the observation group were significantly lower than those in the control group (P<0.05).Conclusion Modified Yulin Decoction is significantly effective in the treatment of POF of spleen and kidney-yang deficiency syndrome.It can significantly improve the level of estrogen, adjust endocrine and relieve clinical symptoms.

Yulin Decoctionpremature ovarian failurespleen and kidney-yang deficiencyhormoneTCM syndrome

焦雨、许文礼

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大同市妇幼保健计划生育服务中心,山西 大同 037000

大同市同煤东周窑医院 中医科,山西 大同 037000

毓麟汤 卵巢早衰 脾肾阳虚 激素 中医症候

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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