多索茶碱与氨茶碱治疗支气管哮喘患者疗效对比
Comparison of the efficacy of Doxofylline and aminophylline in the treatment of bronchial asthma
王海琴 1曹达魁 1姚扬伟1
作者信息
- 1. 嘉兴市第二医院 呼吸科,浙江 嘉兴 314000
- 折叠
摘要
目的 对比分析多索茶碱与氨茶碱治疗支气管哮喘的临床效果.方法 回顾性分析2015年2月～2016年12月间嘉兴市第二医院呼吸科治疗的112例支气管哮喘患者的临床记录资料,将其分为2组:治疗组56例,应用多索茶碱治疗;对照组56例,应用氨茶碱治疗.治疗1 w后,比较2组疗效和不良反应,观察治疗前后的肺功能指标的变化.结果 治疗组、对照组的总有效率分别为91.07%、76.79%,相比差异具统计学意义(P＜0.05);治疗后,治疗组的FVC为(2.24±0.63)L,FEV1为(1.59±0.47)L,VC为(2.94±0.77)L,不良反应发生率为10.71%,均优于对照组,差异均具统计学意义(P＜0.05).结论 多索茶碱治疗支气管哮喘的临床疗效显著,值得临床推广.
Abstract
Objective To compare the clinical effect of Doxofylline and aminophylline in the treatment of bronchial asthma.Methods The clinical data of 112 patients with bronchial asthma treated in Jiaxing Second Hospital from February 2015 to December 2016 were retrospectively analyzed.The patients were divided into two groups: the treatment group(56 cases), the use of doxofylline treatment, and the control group(56 cases), the use of aminophylline treatment.After 1 w treatment, the curative effect and adverse reactions were compared between the two groups to observe the changes of lung function before and after treatment.Results The total effective rate of the treatment group and the control group were 91.07% and 76.79% respectively(P<0.05).After treatment, the FVC of the treatment group was(2.24±0.63)L, FEV1 was(1.59±0.47)L, VC was(2.94±0.77)L, the incidence of adverse reactions was 10.71%, which was superior to the control group, the difference was statistically significant(P<0.05).Conclusion Doxofylline treatment of bronchial asthma clinical efficacy is remarkable, worthy of clinical promotion.
关键词
多索茶碱/氨茶碱/支气管哮喘Key words
doxofylline/aminophylline/bronchial asthma引用本文复制引用
基金项目
2017年浙江省医药卫生技术成果项目(2017ZH022)
出版年
2017
NETL
NSTL
维普
万方数据