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多索茶碱与氨茶碱治疗支气管哮喘患者疗效对比

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目的 对比分析多索茶碱与氨茶碱治疗支气管哮喘的临床效果.方法 回顾性分析2015年2月~2016年12月间嘉兴市第二医院呼吸科治疗的112例支气管哮喘患者的临床记录资料,将其分为2组:治疗组56例,应用多索茶碱治疗;对照组56例,应用氨茶碱治疗.治疗1 w后,比较2组疗效和不良反应,观察治疗前后的肺功能指标的变化.结果 治疗组、对照组的总有效率分别为91.07%、76.79%,相比差异具统计学意义(P<0.05);治疗后,治疗组的FVC为(2.24±0.63)L,FEV1为(1.59±0.47)L,VC为(2.94±0.77)L,不良反应发生率为10.71%,均优于对照组,差异均具统计学意义(P<0.05).结论 多索茶碱治疗支气管哮喘的临床疗效显著,值得临床推广.
Comparison of the efficacy of Doxofylline and aminophylline in the treatment of bronchial asthma
Objective To compare the clinical effect of Doxofylline and aminophylline in the treatment of bronchial asthma.Methods The clinical data of 112 patients with bronchial asthma treated in Jiaxing Second Hospital from February 2015 to December 2016 were retrospectively analyzed.The patients were divided into two groups: the treatment group(56 cases), the use of doxofylline treatment, and the control group(56 cases), the use of aminophylline treatment.After 1 w treatment, the curative effect and adverse reactions were compared between the two groups to observe the changes of lung function before and after treatment.Results The total effective rate of the treatment group and the control group were 91.07% and 76.79% respectively(P<0.05).After treatment, the FVC of the treatment group was(2.24±0.63)L, FEV1 was(1.59±0.47)L, VC was(2.94±0.77)L, the incidence of adverse reactions was 10.71%, which was superior to the control group, the difference was statistically significant(P<0.05).Conclusion Doxofylline treatment of bronchial asthma clinical efficacy is remarkable, worthy of clinical promotion.

doxofyllineaminophyllinebronchial asthma

王海琴、曹达魁、姚扬伟

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嘉兴市第二医院 呼吸科,浙江 嘉兴 314000

多索茶碱 氨茶碱 支气管哮喘

2017年浙江省医药卫生技术成果项目

2017ZH022

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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