中国生化药物杂志2017,Issue(7) :176-177.DOI:10.3969/j.issn.1005-1678.2017.07.068

多囊卵巢综合征患者使用来曲唑与克罗氯米芬促排卵临床对比分析

Comparative analysis on the effect of ovulation induction of letrozole and clomiphene on the treatment of polycystic ovary syndrome

宋小红 费小阳 林珍云 杨晓菁 张頔 美燕
中国生化药物杂志2017,Issue(7) :176-177.DOI:10.3969/j.issn.1005-1678.2017.07.068

多囊卵巢综合征患者使用来曲唑与克罗氯米芬促排卵临床对比分析

Comparative analysis on the effect of ovulation induction of letrozole and clomiphene on the treatment of polycystic ovary syndrome

宋小红 1费小阳 1林珍云 1杨晓菁 1张頔 1美燕1
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作者信息

  • 1. 杭州市妇产科医院 生殖中心,浙江 杭州 310000
  • 折叠

摘要

目的 探讨多囊卵巢综合征患者使用来曲唑与克罗氯米芬促排卵临床排卵效果.方法 选取2014年2月~2015年2月于杭州市妇产科医院就诊的多囊卵巢综合征患者80例作为研究对象,并将其分为2组:对照组和观察组.其中对照组患者采用克罗氯米芬治疗;观察组患者采用来曲唑治疗,比较2组患者的临床疗效.结果 观察组总有效率为95.0%;对照组总有效率为67.5%;两组总有效率的差异有统计学意义(P<0.05).观察组HCG注射日子宫内膜厚度为(9.10±1.32)mm,对照组为(5.38±0.61)mm,2组间差异有统计学意义(P<0.05).结论来曲唑治疗多囊卵巢综合征,临床疗效确切,值得推广.

Abstract

Objective To investigate the effect of ovulation induction of letrozole and clomiphene on the treatment of polycystic ovary syndrome.Methods From February 2014 to February 2014 80 cases with polycystic ovary syndrome in Hangzhou maternity hospitalas the research object were divided into two groups: the control group and the observation group.The control group were treated with clomiphene;the observation group were treated with letrozole.The clinical effect in the two groups were compared.Results The total effective rate was 95.0% in the observation group, which was higher than 67.5% in the control group, the difference was statistically significant(P<0.05).The thickness of endometrium in the observation group was(9.10±1.32)mm and(5.38±0.61)mm in the control group at the HCG injection day, the difference between the two groups was statistically significant (P<0.05).Conclusion Letrozole can be used in the treatment of polycystic ovary syndrome, can get high quality treatment effect, worthy of promotion.

关键词

多囊卵巢综合征/不孕/排卵/来曲唑/克罗氯米芬

Key words

polycystic ovary syndrome/infertility/ovulation/letrozole/clomiphene Kroll

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量7
参考文献量5
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