盐酸米诺环素辅助治疗逆行性牙髓炎的临床疗效分析
Analysis on the effect of minocycline hydrochloride as the auxiliary treatment of patients with retrograde pulpitis
刘敏 1茅菲菲1
作者信息
- 1. 湖州市中心医院 口腔科,浙江 湖州 313000
- 折叠
摘要
目的 探讨盐酸米诺环素辅助治疗逆行性牙髓炎的临床治疗效果.方法 选择2015年1月～2016年12月于湖州市中心医院诊治的逆行性牙髓炎患者90例作为研究对象,根据治疗方案的不同分为对照组和观察组.对照组45例用常规方式联合碘甘油治疗,观察组45例用常规方式联合盐酸米诺环素治疗,比较2组患者各项临床数据.结果 观察组患者治疗后菌斑指数(0.91±0.30)、牙龈出血指数(2.11±1.32)、探诊深度(4.58±1.19)、附着丧失(3.06±1.85)优于对照组患者治疗后菌斑指数(1.38±0.49)、牙龈出血指数(3.07±1.83)、探诊深度(4.87±1.49)、附着丧失(5.18±1.39),组间比较差异有统计学意义(P＜0.05);观察组患者临床治疗效果(95.6%)优于对照组(80.0%),组间比较差异有统计学意义(P＜0.05);观察组患者不良反应发生率(6.7%)低于对照组(17.8%),组间比较差异有统计学意义(P＜0.05).结论 常规治疗联合盐酸米诺环素治疗逆行性牙髓炎患者的临床效果显著,可有效改善患者各项临床症状,值得临床上广泛使用.
Abstract
Objective To study the clinical effect of minocycline hydrochlorideointment on the treatment of patients with retrograde pulpitis.Methods From January 2015 to December 2016 in Huzhou central hospital, 90 cases with retrograde pulpitis as the research object were divided into two groups, the control group and the observation group, 45 cases in each group.The control group were received conventional treatment combined with iodine glycerin, and the observation group were given conventional treatment combined with minocycline hydrochloride ointment.The clinical data were compared in the two groups.Results After treatment, plaque index(0.91±0.30), gingival bleeding index(2.11±1.32), explore clinical depth(4.58±1.19)and attachment loss(3.06±1.85)in the observation group were better than the plaque index(1.38±0.49), gingival bleeding index(3.07±1.83),explore clinical depth(4.87±1.49)and attachment loss(5.18±1.39)in the control group, the difference between the two groups was statistically significant(P< 0.05);the clinical effect 95.6% in the observation group was better than 80.0% in the control group(P< 0.05).The adverse reaction rate was 6.7% in the observation group, which was lower than 17.8% in the control group(P< 0.05).Conclusion It that the conventional method combined with minocycline hydrochloride ointment on the treatment of retrograde pulpitis has significant clinical effect, can effectively improve the clinical symptoms of patients, is worthy of clinical application.
关键词
盐酸米诺环素/辅助治疗/逆行性牙髓炎Key words
minocycline hydrochloride/adjuvant therapy/retrograde odontitis引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据