经皮椎体后凸成形术联合阿仑膦酸钠对患者心理干预治疗老年骨质疏松性椎体压缩性骨折的疗效
Percutaneous kyphoplasty combined with alendronate in the treatment of osteoporotic vertebral compression fractures in patients with psychological intervention
王杨丹 1王演1
作者信息
- 1. 乐清市第二人民医院 骨一科,浙江 乐清 325608
- 折叠
摘要
目的 探讨分析经皮椎体后凸成形术联合阿仑膦酸钠对患者心理干预治疗老年骨质疏松性椎体压缩性骨折的临床效果.方法 将乐清市第二人民医院2014年4月～2016年9月收治的200例老年骨质疏松性椎体压缩性骨折患者作为研究对象,并将患者随机分为对照组和研究组,各100例,对照组采用皮椎体后凸成形术进行治疗,研究组在对照组的基础上采用口服阿仑膦酸钠片进行治疗,采用视觉模拟评分法(VAS)对2组术后1 d、3个月及6个月的疼痛缓解程度进行评估.结果 2组患者在术后1 d及3个月时VAS评分无显著差异性,术后6个月时研究组患者VAS评分及疼痛改善明显优于对照组(P＜0.05),比较差异有统计学意义;与术前相比,2组患者治疗后VAS评分比较差异具有统计学意义(P＜0.05);研究组患者有2例口服阿仑膦酸钠患者出现轻微胃肠道刺激反应.结论 经皮椎体后凸成形术联合阿仑膦酸钠对患者心理干预治疗老年骨质疏松性椎体压缩性骨折具有很好的治疗效果,能有效减轻疼痛,提高患者的生活质量,具有安全可行性,值得在临床上推广应用.
Abstract
Objective To investigate the analysis of percutaneous kyphoplasty combined with alendronate intervention clinical curative effect of the treatment of osteoporotic vertebral compression fractures in patients with psychological.Methods In Second People's Hospital of Yueqing City from April 2014 to September 2016 were 200 cases of osteoporotic vertebral compression fracture patients as the research object, and the patients were randomly divided into the control group and the study group, each with 100 cases, the control group used percutaneous kyphoplasty for treatment, the study group were treated with oral administration of Alendronate Sodium Enteric-coated Tablets on the basis of the control group, using the visual analogue scale(VAS) of the two groups after 1 Day, 3 months and 6 months of the degree of pain relief was assessed.Results Two groups of patients on the 1 postoperative day and 3 months VAS score had no significant difference, 6 months after operation of patients with VAS score and pain improved significantly better than the control group(P<0.05), the difference was statistically significant;compared with the preoperative VAS score of the two groups compared with statistical significance(P<0.05);the study group 2 cases of patients with oral alendronate in patients with mild gastrointestinal irritation.Conclusion Percutaneous vertebroplasty combined with alendronate sodium on patients with psychological intervention in the treatment of senile osteoporotic vertebral compression fractures achieved good results, which can effectively relieve pain, improve the quality of life and daily life ability of patients, is worthy of further clinical application.
关键词
经皮椎体后凸成形术/阿仑膦酸钠/骨质疏松/椎体压缩性骨折/疗效Key words
percutaneous kyphoplasty/alendronate/osteoporosis/vertebral compression fractures/clinical efficacy引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据