首页|神经外科术后颅内感染的危险因素分析及万古霉素的治疗效果研究

神经外科术后颅内感染的危险因素分析及万古霉素的治疗效果研究

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目的 分析神经外科术后颅内感染的危险因素并探讨万古霉素的治疗效果.方法 本研究以宁波市第一 医院2011年1月~2014年7月期间收治的28例开颅手术后发生颅内感染的患者作为本次研究对象,回顾性分析其年龄、性别、急诊、基础疾病、乳突气房、脑室引流、后颅窝手术、再次手术和手术时间(≥4 h)等临床资料,总结神经外科术后颅内感染危险因素并观察万古霉素治疗此类患者的临床效果.结果 术中开放乳突气房、再次手术、脑室引流和手术时间(≥4 h)为颅内感染的高危因素.28例开颅手术后颅内感染患者经万古霉素治疗总有效率100.00%.结论 神经外科术后颅内感染高危因素包括术中开放乳突气房、再次手术、脑室引流和手术时间较长等,万古霉素是治疗神经外科颅内感染的有效药物.
Analysis on the risk factors of intracranial infection after neurosurgery and the therapeutic effect of vancomycin
Objective To analyze the risk factors of intracranial infection after neurosurgery and the effect of vancomycin.Methods 28 cases of craniotomy in this study, The First Hospital of Ningbo City from January 2011 to July 2014 during the years after the occurrence of intracranial infection patients as the research object, a retrospective analysis of the age, gender, emergency, basic diseases, mastoid airroom, ventricle drainage, posterior fossa surgery, reoperation and operation time (more than 4h).The clinical data, summarize the risk factors of postoperative intracranial infection in department of neurosurgery and to observe the clinical effect of vancomycin in the treatment of such patients.Result The high risk factors of intracranial infection include: Open mastoid gas room during operation, ireoperation, ventricular drainage and operative time (more than 4h).In 28 cases with intracranial infection after craniotomy, the total effective rate of vancomycin treatment was 100.00%.Conclusion The high risk factors of intracranial infection after operation include open surgery, mastoid room, reoperation, ventricular drainage and longer operation time.Vancomycin is an effective drug in the treatment of intracranial infection in the department of neurosurgery.

neurosurgerycraniotomyintracranial infectionrisk factorsvancomycin

张丹丹、周斌、朱红

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宁波市第一医院 手术室,浙江 宁波 315010

宁波出入境检验检疫局 旅检科,浙江 宁波 315010

神经外科 开颅手术 颅内感染 危险因素 万古霉素

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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