首页|地诺前列酮、米索前列醇及缩宫素用于促宫颈成熟及引产的对比研究

地诺前列酮、米索前列醇及缩宫素用于促宫颈成熟及引产的对比研究

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目的 分析地诺前列酮、米索前列醇及缩宫素用于促宫颈成熟及引产的效果.方法 将本院在2015年1月~2017年1月期间接受待产的120例孕妇选取为本次的研究对象,将所有的孕妇按照随机数字表法分为3组,分别为地诺前列酮组、米索前列醇组、缩宫素组,每组40例.地诺前列酮组将地诺前列酮放置在孕妇阴道后穹窿,米索前列醇组将米索前列醇放置在孕妇阴道后穹窿,缩宫素组使用缩宫素治疗,静脉注射缩宫素.对比3组孕妇分别使用不同方法治疗后的分娩时间、破膜时间和临产时间以及引产成功率.结果 地诺前列酮组分娩时间、破膜时间和临产时间均明显的短于其他两组,差异具有统计学意义(P<0.05);地诺前列酮组孕妇的引产成功率显著高于缩宫素组,2组间相比,差异具有统计学意义(P<0.05);地诺前列酮组未出现异常情况,不良反应较少.结论 使用地诺前列酮促宫颈成熟及引产的效果较为显著,相比米索前列醇与缩宫素,不良反应少,安全性相对较高,值得推广应用.
Study on the effect of dinoprostone, misoprostol and oxytocin on the treatment of cervical ripening and labor induction
Objective To compare and analyze the effect of dinoprostone misoprostol and oxytocin in cervical ripening and labor induction.Methods 120 pregnant women in labor in our hospital from January 2015 to January 2017 were selected as the object in this study, all pregnant women were randomly divided into 3 groups, respectively dinoprostone group, misoprostol group and oxytocin group, 40 pregnant in each group., Dinoprostone was placed in vaginal fornix in dinoprostone group;misoprostol was placed in vaginal fornix in misoprostol group;Oxytocin was injected in oxytocin group.The delivery time, rupture time of fetal membranes, labor time and successful rate of induced labor in the 3 groups were compared.Results The dinoprostone group after treatment in pregnant women take delivery time,time and labor rupture time were significantly shorter than the other two groups(P<0.05),the difference was statistically significant;dinoprostone group of pregnant women, the success rate was significantly higher than that of oxytocin group, compared between the two groups(P<0.05),with statistical significance difference;dinoprostone group did not appear abnormal, less adverse reaction.Conclusion Dinoprostone used for cervical ripening and labor induction, the effect is significant, compared with misoprostol and oxytocin, less adverse reaction, high safety, and is worthy of popularization and application.

dinoprostonemisoprostoloxytocincervical ripeninginduced abortion

鲍南男、蔡惠燕

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宁波市第四人民医院 妇产科,浙江 宁波 315700

象山县中医院 妇产科,浙江 宁波 315700

地诺前列酮 米索前列醇 缩宫素 宫颈成熟 引产

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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