糖尿乐胶囊辅助二甲双胍对初诊2型糖尿病患者血糖、尿糖及胰岛素抵抗水平的影响
Effect of Tangniaole capsule combined with metformin on the blood glucose, urine glucose and insulin resistance in patients with newly diagnosed type 2 diabetes mellitus
陶东红 1刘潇2
作者信息
- 1. 青海省西宁市第一人民医院 临床药学科,青海 西宁 810000
- 2. 青海省人民医院 药学部,青海 西宁 810007
- 折叠
摘要
目的 探讨糖尿乐胶囊辅助二甲双胍在初诊2型糖尿病(T2DM)患者中的应用价值.方法 将本院收治的120例初诊T2DM患者分为对照组与观察组,对照组采用二甲双胍治疗,观察组加用糖尿乐胶囊治疗.比较2组治疗前后症状体征、血糖、尿糖、胰岛素抵抗指数(HOMA-IR)、胰岛素分泌功能(HOMA-β)的变化,统计不良反应发生率.结果 观察组疗效优于对照组(P＜0.05),且其治疗后症状及体征积分、血糖、糖化血红蛋白(HbA1c)、24 h尿糖定量、HOMA-IR水平均低于对照组,HOMA-β高于对照组(P＜0.05).结论 糖尿乐胶囊辅助二甲双胍治疗初诊T2DM患者疗效肯定,可降血糖、尿糖,减轻胰岛素抵抗.
Abstract
Objective To investigate the application value of Tangniaole capsule combined with metformin in patients with newly diagnosed type 2 diabetes mellitus (T2DM).Methods 120 cases of patients with newly diagnosed T2DM were divided into the control group and the observation group.The control group was treated with metformin while the observation group was additionally treated with Tangniaole capsule.Symptoms and signs, changes in blood glucose, urine glucose, insulin resistance index (HOMA-IR) and insulin secretion (HOMA-β) were compared between the two groups.The incidence of adverse reactions was statistically analyzed.Results The curative effect in the observation group was better than control group (P<0.05).After treatment, scores of symptoms and signs, blood glucose, glycosylated hemoglobin (HbA1c), 24 h urine glucose quantitation and HOMA-IR were lower, and HOMA-β was higher in the observation group than in the control group (P<0.05).Conclusion Tangniaole capsule combined with metformin is effective in the treatment of newly diagnosed T2DM, and it can reduce blood glucose, urine glucose and insulin resistance.
关键词
2型糖尿病/糖尿乐胶囊/胰岛素抵抗Key words
type 2 diabetes mellitus/tangniaole capsule/insulin resistance引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据