缬沙坦联合贝那普利治疗充血性心力衰竭的临床研究
Clinical study of valsartan combined with benazepril in the treatment of congestive heart failure
张建强 1漆波1
作者信息
- 1. 江油市九○三医院 重症医学科,四川 江油 621700
- 折叠
摘要
目的 分析缬沙坦联合贝那普利在充血性心力衰竭中的治疗价值.方法 纳入江油市九○三医院收治的102例充血性心力衰竭患者进行研究,随机分成对照组、观察组各51例.2组均予以强心利尿、抗感染等基础治疗,对照组在基础治疗上予以贝那普利治疗,观察组在对照组治疗基础上加用缬沙坦,比较2组治疗效果,并检测治疗前后心功能指标变化情况.结果 对照组有效率80.39%,明显低于观察组96.08%(P＜0.05);治疗后,观察组LVEF显著升高,LVESd、LVEDd显著下降,且各指标均明显优于对照组(P＜0.05).结论 缬沙坦联合贝那普利治疗充血性心力衰竭能有效改善临床症状,显著提升心功能,值得临床推广.
Abstract
Objective To analyze the therapeutic values of valsartan combined with benazepril in the treatment of patients with congestive heart failure.Methods 102 cases of patients with congestive heart failure in Nine 0 Third Hospital were enrolled in the study.They were randomly divided into the control group and the observation group, with 51 cases in each group.Both groups were given cardiac diuretic, anti-infection and other basic treatment and the control group was given benazepril on the basis of basic treatment while the observation group was additionally given valsartan on the basis of treatment in the control group.The curative effects were compared and the changes of cardiac function indexes were detected before and after treatment between the two groups.Results The effective rate of treatment was 80.39% in the control group, which was lower than that in the observation group with 96.08% (P<0.05).After treatment, the observation group LVEF increased significantly, LVESd and LVEDd decreased significantly, and each index was significantly better than that of the control group (P<0.05).Conclusion Valsartan combined with benazepril in the treatment of congestive heart failure can effectively relieve the clinical symptoms and improve the cardiac function, therefore it is worthy of clinical promotion.
关键词
充血性心力衰竭/贝那普利/缬沙坦/心功能Key words
congestive heart failure/benazepril/valsartan/cardiac function引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据