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反复发作化脓性胆管炎并肝内胆管细胞癌MRI表现分析

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目的 探讨反复发作化脓性胆管炎并肝内胆管细胞癌(ICC)患者的MRI表现特征及临床诊断价值.方法 选取2010年6月~2014年7月收治的264例反复发作化脓性胆管炎患者为研究对象,均予以磁共振成象(MRI)检查、外科手术病理检查或穿刺活检.其中经外科手术病理检查结果证实合并肝内胆管细胞癌者43例(52个病灶),以病理检查结果为"金标准"评估MRI检查对反复发作化脓性胆管炎并肝内胆管细胞癌临床诊断的准确性、特异性及敏感性;分析其MRI表现.结果 此次入组的264例反复发作性化脓性胆管炎患者中,经外科手术病理检查或穿刺活检确诊合并肝内胆管细胞癌者43例(52个病灶),占总受试人数的16.3%;MRI检查结果显示真阴性218例,真阳性41例,假阴性2例,假阳性3例,诊断敏感性为95.3%(41/43),特异性为98.6%(218/221),准确性为98.1%(259/264).结论 MRI诊断反复发作化脓性胆管炎并肝内胆管细胞癌具有较高的准确性、特异性及敏感性,MRI特征明显,值得临床推广.
Analysis of MRI findings of recurrent supurative colangitis complicated by intrahepatic cholangiocarcinoma
Objective To investigate the MRI findings of recurrent supurative colangitis complicated by intrahepatic cholangiocarcinoma and clinical diagnostic value.Methods 264 patients with recurrent suppurative cholangitis who were admitted into the hospital during June 2010 to July 2014 were selected as the research objects.All of the patients were given magnetic resonance imaging(MRI)and surgical pathological examination or biopsy.The Results of surgical pathological examination certified that there 43 patients(52 lesions)complicated by intrahepatic cholangiocarcinoma.The results of pathological examination were taken as the golden standard to evaluate the accuracy, specificity and sensitivity of MRI in the clinical diagnosis of recurrent supurative colangitis complicated by intrahepatic cholangiocarcinoma.The MRI findings were analuzed.ResultsAmong the 264 patients with recurrent supurative cholangitis in this group, there were 43 patients(52 lesions)with complicated intrahepatic cholangiocarcinoma confirmed by surgical pathological examination or biopsy, accounting for 16.3% of total number of subjects;MRI results showed that 218 cases were true negative, 41 cases true positive, 2 cases false negative and 3 cases false positive.The diagnostic sensitivity was 95.3%(41/43), specificity 98.6%(218/221)and the accuracy 98.1%(259/264).Conclusion MRI in the diagnosis of recurrent supurative cholangitis complicated by intrahepatic cholangiocarcinoma is of higher accuracy, sensitivity and specificity.MRI findings are obvious.It is worthy of clinical promotion.

recurrentsuppurative cholangitisintrahepatic cholangiocarcinomaMRI findings

郭晓军、刘源远、张玲、张长江

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海军青岛第二疗养院 干部二科,山东 青岛 266000

海军青岛第二疗养院 特勤一科,山东 青岛 266000

第二军医大学附属长海医院 消化内科,上海 200433

第三军医大学附属西南医院 传染病专科医院,重庆 400038

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反复发作 化脓性胆管炎 肝内胆管细胞癌 MRI表现

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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