首页|抗抑郁药联合α受体阻滞剂在治疗慢性前列腺炎中的临床应用

抗抑郁药联合α受体阻滞剂在治疗慢性前列腺炎中的临床应用

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目的 探讨抗抑郁药联合α受体阻滞剂在治疗慢性前列腺炎中的临床应用效果.方法 选择2016年1月~2016年12月本院收治的慢性前列腺炎患者90例,按照随机数字表分为对照组和研究组,各45例,其中对照组采用α受体阻滞剂联合维生素C治疗,研究组采用抗抑郁药联合α受体阻滞剂治疗.记录2组治疗前后NIH-CPSI评分、SDS评分,并比较2组治疗效果.结果 治疗前,2组NIH-CPSI评分、SDS评分比较差异无统计学意义,治疗后,2组NIH-CPSI评分、SDS评分均显著优于治疗前,且研究组明显优于对照组,差异有统计学意义(P<0.05);研究组症状总有效率(91.1%)高于对照组(71.1%),抑郁总有效率(93.3%)高于对照组(73.3%),差异有统计学意义(P<0.05).结论 抗抑郁药联合α受体阻滞剂在慢性前列腺炎治疗中效果显著,利于患者临床症状的缓解,并使其抑郁症状得到明显改善,因此具有较好的临床应用价值,值得进一步推广.
Clinical application of antidepressant combined with α-blocker in the treatment of chronic prostatitis
Objective To investigate the clinical effect of antidepressants combined with α-blockers in the treatment of chronic prostatitis.Methods A retrospective analysis of 90 cases of chronic prostatitis treated in our hospital from January 2016 to December 2016 was divided into two groups according to the random number table.The control group was treated with α-blocker Combined with vitamin C treatment, the study group using antidepressants combined with α-blockers treatment.The NIH-CPSI score and SDS score were recorded before and after treatment, and the therapeutic effects were compared between the two groups.Results There were no significant differences in NIH-CPSI scores and SDS scores between the two groups.After treatment, the scores of NIH-CPSI and SDS were significantly better than those before treatment, and the study group was superior to the control(91.1%) was higher than that of the control group(71.1%), the total effective rate of depression(93.3%) was higher than that of the control group(73.3%), and the total effective rate was 91.1%, The difference was statistically significant(P<0.05),comparable.Conclusion Antidepressants combined with α-blockers are effective in the treatment of chronic prostatitis, which is beneficial to the alleviation of clinical symptoms and the improvement of their symptoms.Therefore, it has a good clinical value and worthy of further popularization.

antidepressantsα-blockerschronic prostatitis

徐啸、满立波、李贵忠

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北京积水潭医院 泌尿外科,北京 100096

抗抑郁药 α受体阻滞剂 慢性前列腺炎

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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