摘要
目的 探讨急性脑卒中患者下呼吸道多重耐药菌(MDR)感染的危险因素.方法 回顾性分析2013年1月～2015年12月期间本院收治的170例急性脑卒中患者完整临床资料,按是否合并下呼吸道MDR感染分别纳入MDR感染组和非MDR感染组,每组各85例.应用统计学软件进行单因素分析和多因素logistic回归分析,探讨急性脑卒中患者MDR感染的危险因素.结果 单因素分析:患者吸烟、合并COPD、昏迷、脑出血、咳呛、咳嗽反射差、气管插管、留置尿管、留置胃管、2种以上抗生素联合应用＞5 d与MDR感染关系密切(P＜0.05);多因素logistic回归分析:合并COPD、昏迷、气管插管、脑出血、2种以上抗生素预防性应用是MDR感染的独立危险因素.结论 急性脑卒中患者下呼吸道MDR感染与患者自身因素及医源性因素相关,合并COPD、昏迷、气管插管、脑出血、抗生素的不合理应用是其发生的独立危险因素.
Abstract
Objective To investigate the acute stroke patients with lower respiratory tract of multi drug resistant bacteria(MDR) infection risk factors.Methods The clinical data of 170 patients with acute stroke were retrospectively analyzed from January 2013 to December 2015.The MDR infection was divided into MDR infection group and non-MDR infection group.example.Univariate analysis and multivariate logistic regression analysis were used to analyze the risk factors of MDR infection in patients with acute stroke.Results Univariate analysis: The relationship between COPD, coma, cerebral hemorrhage, cough, cough reflex, tracheal intubation, indwelling catheter, indwelling gastric tube, and combination of two or more antibiotics was more than 5 days and MDR infection(P<0.05).Multivariate logistic regression analysis: COPD, coma, tracheal intubation, cerebral hemorrhage, two or more antibiotics prophylactic use is an independent risk factor for MDR infection.Conclusion The acute stroke patients with lower respiratory tract infection in patients with MDR factors and iatrogenic factors, combined with COPD, coma, tracheal intubation, cerebral hemorrhage, irrational use of antibiotics are independent risk factors for its occurrence.
NETL
NSTL
维普
万方数据