首页|心理疏导联合早期双抗干预对急性脑梗死预后的影响分析

心理疏导联合早期双抗干预对急性脑梗死预后的影响分析

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目的 分析心理疏导联合早期双抗干预对急性脑梗死预后的影响.方法 选取本院神经内科2014年2月~2016年3月收诊的76例急性脑梗死的患者,根据其入院顺序进行编号,偶数为观察组,奇数为对照组,各38例.对照组患者早期给予拜阿司匹林、氯吡格雷双抗干预,观察组在对照组基础上另给予心理疏导.记录并分析2组患者预后情况.结果 观察组治疗后1个月神经功能缺损评分(NIHSS)和简易智能精神状态评分(MMSE)分别为(9.16±0.73)分、(25.42±2.00)分,均优于对照组(12.59±1.05)分、(20.73±2.16)分,且差异均具有显著性(P<0.05).观察组治疗后2个月日常生活活动能力指数(Barthel)和汉密顿抑郁评分(HAMD)分别为(80.86±3.29)分、(13.70±1.53)分,均优于对照组(71.53±3.75)分、(18.53±1.99)分,且差异均具有显著性(P<0.05).观察组治疗期间总不良反应为18.42%,略高于对照组14.29%,但差异无统计学意义.结论 心理疏导联合早期双抗干预对急性脑梗死患者预后情况有积极意义.
Anaysis on the effect of prognosis of psychological counseling combined with early double anti antiplatelet on the treatment of the patients with acute cerebral infarction
Objective To analyze the effect of prognosis of psychological counseling combined with early double anti antiplatelet on the treatment of acute cerebral infarction.Methods 76 patients with acute cerebral infarction who were admitted to our hospital from February 2014 to March 2016 were numbered according to their admission order.The patients with even numbers were in the observation group and with the odds number in the control group, 38 cases in each group.The control group were given aspirin and clopidogrel in the early stage, and the observation group were given psychological guidance on the basis of the control group.The prognosis in the two groups was recorded and analyzed.Results The neurological deficit score (NIHSS) and simple mental state score (MMSE) in the observation group (9.16±0.73)points, (25.42±2.00)points were significantly higher in the observation group than those in the control group (12.59±1.05)points, (20.73±2.16)points.And the differences were significant (P<0.05).The level of dailyliving activity index (Barthel) and Hamilton depression (HAMD) in the observation groupwere (80.86±3.29)points, (13.70±1.53)points, respectively, which were better than those in the control group (71.53±3.75)points, (18.53±1.99)points, and the differences were significant (P<0.05).The total adverse reaction rate in the treatment group was 18.42%, slightly higher than 14.29% in the control group, but the difference was not statistically significant.Conclusion Psychological counseling combined with early double antiplatelet intervention has positive effect on the prognosis in the patients with acute cerebral infarction.

cerebral infarctionneurological deficitpsychological counseling

赵然、刘莉

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首都医科大学附属北京天坛医院 神经重症医学科,北京 100050

建宫医院 神经内科,北京 100054

脑梗死 神经功能缺损 心理疏导

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(7)
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