银杏叶提取物片联合丁苯酞软胶囊对阿尔茨海默病的疗效及安全性观察
Efficacy and safety of ginkgo biloba extract tablets combing with Butyphthalide to alzheimer disease
许丹艳1
作者信息
- 1. 东阳市人民医院 药剂科,浙江 东阳 322100
- 折叠
摘要
目的 观察银杏叶提取物片联合丁苯酞软胶囊对阿尔茨海默病(AD)的疗效及安全性.方法 选取2015年1月~2016年4月72例AD患者分为对照组与观察组,各36例.均给予丁苯酞治疗,观察组另给予银杏叶提取物片.结果 治疗后,观察组总有效率为86.11%,高于对照组63.89%(P<0.05),相关量表得分以及血浆NO和血清VEGF和MDA水平均优于对照组(P<0.05).对照组出现13.89%的不良反应,高于观察组8.33%,但差异无统计学意义.结论 银杏叶提取物片能提高阿尔茨海默病的治疗效果,不良反应少.
Abstract
Objective To observe efficacy and safety of ginkgo biloba extract tablets combing with butyphthalide to alzheimer disease(AD). Methods 72 patients with AD in our hospital from January 2015 -April 2016 were selected,and randomly divided into observation group and control group,36 cases in each groups..Two groups were given butylphthalide treatment,and observation group were given plus ginkgo biloba extract tablets. Results Afte treatment,effective rate of observation group was 86.11%,higher than control group 63.89%(P<0.05).Correlation scale score and plasma NO,serum VEGF and MDA level of observation group were better than control group(P<0.05).In adverse reaction,compared with observation group 8.33%,control group was 13.89%. Conclusion Ginkgo biloba extract tablets can improve the therapeutic effect of alzheimer disease and have less adverse reactions.
关键词
银杏叶提取物/丁苯酞/阿尔茨海默病Key words
ginkgo biloba extract tablets/butyphthalide/alzheimer disease引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据