首页|宫腔镜手术中舒芬太尼与瑞芬太尼复合丙泊酚麻醉的效果对比

宫腔镜手术中舒芬太尼与瑞芬太尼复合丙泊酚麻醉的效果对比

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目的 研究宫腔镜手术中舒芬太尼复合丙泊酚与瑞芬太尼复合丙泊酚麻醉效果,为临床手术麻醉方式选择提供科学参考依据.方法 以手术麻醉方式不同作为研究分组依据,2016年11月~2017年3月94例在丽水市中心医院行宫腔镜手术的患者被均分为观察组与对照组,每组47例.取1μg/kg剂量瑞芬太尼复合2 mg/kg剂量丙泊酚通过静脉泵注的方式给药麻醉对照组患者,取0.2μg/kg剂量舒芬太尼复合2 mg/kg丙泊酚通过静脉注射给药麻醉观察组患者.对照比较2组患者麻醉前、麻醉后2 min、手术开始后10 min、术毕10 min平均动脉(MAP)、呼吸(RR)、脉搏血氧饱和度(SpO2)、心率(HR)指标值,记录2组麻醉起效时间、术后苏醒时间、定向力恢复时间、Ramsay镇静评分.结果 与麻醉前比较,麻醉后2组患者MAP、RR、SpO2、HR显著降低,麻醉前后差异有统计学意义(P<0.05),组间上述指标差异无统计学意义;手术结束后10 min组间MAP、HR指标值比较,观察组优于对照组,2组差异有统计学意义(P<0.05).麻醉起效时间、术后苏醒时间、定向力恢复时间、Ramsay镇静评分组间差异无统计学意义;观察组VAS评分显著低于对照组(P<0.05).结论宫腔镜手术中采用舒芬太尼复合丙泊酚麻醉,能较好维持患者生命体征稳定,有效减轻患者术后疼痛反应.
Comparison on the effect of sufentanil and remifentanil combined with propofol anesthesia in hysteroscopic surgery
Objective To compare the anesthetic effect of sufentanil combined with propofol and remifentanil combined with propofol in hysteroscopic surgery, and to provide a scientific basis for the selection of clinical anesthesia methods. Methods From November 2016 to March 2017, 94 patients in Lishui central hospital underwent hysteroscopic surgery were divided into the observation group and the control group according the anesthesia way, 47 cases in each group. The control group were given remifentanil(1 μg/kg) combined with propofol(2 mg/kg) by intravenous injection, the observation group were given sufentanil(0.2 μg/kg) combined with propofol(2 mg/kg). The mean arterial pressure(MAP), respiration (RR), pulse oxygen saturation (SpO2), heart rate (HR), the onset time of anesthesia, the postoperative recovery time, the recovery time of orientation and Ramsay sedation score in the two groups were recorded and compared before anesthesia, 2 min after anesthesia, 10 min after operation, 10min after operation finished. Results Compared with before anesthesia, MAP, RR, SpO2, HR index decreased significantly after anesthesia, the differences have statistical significance (P<0.05), the control group compared to the index value, the observation group and the control group of convergence and the decline of difference, group showed no statistically significant difference the observation group was more stable; comparison between the 10min group and MAP HR index after surgery, there was significant difference between two groups (P<0.05). The onset time of anesthesia, postoperative recovery time, orientation recovery time, Ramsay score difference between the groups was not statistically significant sedation score difference was statistically significant between group VAS, observation group than in the control group (P<0.05). Conclusion Sufentanil combined with propofol anesthesia were used in hysteroscopic surgery, which can better maintain the vital signs of patients, effectively reduce postoperative pain.

sufentanilremifentanilpropofolhysteroscopic surgeryanesthesia

卢巧玲、周洁、叶华民、雷李培

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丽水市中心医院 麻醉科,浙江 丽水 323000

舒芬太尼 瑞芬太尼 丙泊酚 宫腔镜手术 麻醉

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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