首页|苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果对比

苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果对比

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目的 研究分析苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果对比.方法 选取本院2015年1月~2016年12月收治的100例高血压患者为研究对象,随机分为对照组和实验组2组,每组患者各为50例.对照组患者进行苯磺酸氨氯地平治疗,实验组患者进行苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗.比较分析实验组与对照组患者的治疗效果.结果 经过对应的治疗后,实验组50例患者中,总有效例数为44例,6例患者无效,治疗总有效率为88.0%.对照组50例患者中,总有效例数为37例,13例患者无效,治疗总有效率为74.0%.可得,实验组患者的治疗效果显著高于对照组患者,差异具有统计学意义(P<0.05).实验组患者不良反应发生例数为5例,3例患者出现面部潮红,2例患者出现疼痛,发生率为10.0%.对照组患者不良反应发生例数为12例,5例患者出现踝部水肿,7例患者出现头痛,发生率为24.0%.可得,对照组患者发生不良反应率显著高于实验组,差异具有统计学意义(P<0.05).结论 苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压能够在很大程度上提高治疗有效率,安全性较高,不良反应概率较低,具有临床进一步推广和应用的意义.
Comparison of amlodipine besylate and amlodipine besylate in the treatment of hypertension
Objective To study and analyze the effect of amlodipine besylate and amlodipine besylate in the treatment of hypertension. Methods 100 patients with hypertension treated in our hospital from January 2015 to December 2016 were selected and randomly divided into two groups, the control group and the experimental group, with 50 patients in each group. The control group was treated with amlodipine besylate, and the patients in the experimental group were treated with amlodipine besylate and amlodipine besylate. The therapeutic effects of the experimental group and the control group were compared and analyzed. Results After the corresponding treatment, the experimental group of 50 cases, the total effective number of 44 cases, 6 patients invalid, the total effective rate was 88%. In the control group of 50 cases, the total effective number was 37 cases, 13 cases were invalid, the total effective rate was 74%. The treatment effect of the experimental group was significantly higher than that of the control group, with statistical difference (P<0.05). There were 5 cases of adverse reactions in the experimental group, 3 patients had facial flushing, and 2 patients suffered from pain. The incidence was 10%. The number of adverse reactions in the control group was 12 cases, ankle edema occurred in 5 patients, and headache occurred in 7 patients, with a rate of 24%. The rate of adverse reactions in the control group was significantly higher than that in the experimental group, with statistical difference (P<0.05). Conclusion Amlodipine and Levamlodipine besylate in treatment of hypertension can improve the treatment efficiency to a great extent, high safety, low probability of adverse reactions, with further clinical promotion and application significance.

Amlodipine Besylateamlodipine besylatehypertensiontreatment effect

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绍兴市立医院 综合内科,浙江 绍兴 312000

苯磺酸氨氯地平 苯磺酸左旋氨氯地平 高血压 治疗效果

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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