三种药物疗法在广泛性焦虑症患者中的临床效果观察及对患者心理波动的影响研究
Clinical observation of three drug therapies in patients with generalized anxiety disorder and its effect on psychological fluctuation
李发明 1杨景志 2刘建洪 1黄燕1
作者信息
- 1. 云南省传染病专科医院 精神三科,云南 昆明 650301
- 2. 云南省大理州精神病院,云南 大理 671000
- 折叠
摘要
目的 探讨三种药物疗法在广泛性焦虑症患者中的临床效果及心理状态改善情况.方法 选取2015年1月~2016年12月于本院诊治的广泛性焦虑症患者90例,此次依不同治疗方式分为观察A组、观察B组、观察C组,各30例.观察A组用文拉法辛治疗,观察B组用坦度螺酮治疗,观察C组用劳拉西泮治疗;全面观察3组患者临床治疗情况、心理状态改善情况、不良反应发生情况、用药依从性情况,严格记录所获相关数据并作对比分析.结果 3组患者临床治疗效果比较,差异无统计学意义;观察A组患者心理状态改善情况优于观察B、C组,不良反应发生率低于观察B、C组,用药依从性高于观察B、C组,差异有统计学意义(P<0.05).结论 文拉法辛对患者心理状态改善程度更为显著,发生不良反应者少,患者用药依从性高,值得临床上广泛应用.
Abstract
Objective To investigate the clinical efficacy and psychological status of three kinds of drug therapy in patients with generalized anxiety disorder. Methods 90 patients with generalized anxiety disorder in our hospital from January 2015 to December 2016 were selected,and according to the different treatment methods divided into the observation group A, observation group B and observation group C,45 cases in each groups. The observation group A with venlafaxine treatment, observation group B with tandospirone treatment, observation group C treated with Laura Si; comprehensive observation of 3 groups of patients with clinical treatment, improve psychological status and the incidence of adverse reactions, drug compliance, strict record the relevant data and comparative analysis. Results 3 groups of patients with clinical curative effect, no significant difference ; observation group A patients psychological status were better than those observed in B and C group. The incidence of adverse reaction was lower than observed in B and C group, medication compliance was higher than B, C group, the difference was statistically significant (P<0.05). Conclusion The patients with generalized anxiety disorder can choose Vin Rafa Sin, tandospirone, Laura Si treatment, but Vin Rafa Sin on the psychological status of patients with improvement is more significant, less adverse reactions, medication compliance of patients, is worthy of clinical application.
关键词
文拉法辛/坦度螺酮/劳拉西泮/广泛性焦虑症/心理波动Key words
vin rafa sin/tandospirone/lorazepam/generalized anxiety disorder/psychological fluctuation引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据