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心内科五类抗高血压药物的临床应用

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目的 研究分析心内科五类抗高血压药物的临床应用.方法 选取浙江中医药大学附属富阳区第一医院2015年1月~2016年12月收治的100例需口服抗高血压药物的心血管科患者为本次研究的研究对象,回顾分析患者的临床资料,研究患者的服药情况,系统分析所选的患者的用药情况,包括患者的用药名称和所属的类别,记录每日服用的具体剂量以及联用药物的情况.利用用药频数指标和药物利用指标为参数进行评价.合理用药的标准即药物利用指数<1.结果 经过相应的分析后,可得利尿药物的使用例数为32例,使用率为32.0%.β 受体阻断药物的使用例数为28例,使用率为28.0%.钙拮抗药物类的使用例数为20例,使用率为20.0%.血管紧张素转换酶抑制剂药物使用例数为14例,使用率为14.0%.血管紧张素Ⅱ受体阻滞剂药物使用例数为6例,使用率为6.0%.五类抗高血压药物使用率前三分别为利尿药物、β受体阻断药物以及钙拮抗药物.美托洛尔用药频率最高,为25.0%.呋塞咪用药例数为13例,用药频率为13.0%.硝苯地平缓释片药物的用药例数为12例,用药频率为12.0%.经过研究可得,高血压联合用药中,二联或者三联的用药方案较多.氢氯噻嗪片与氨氯地平片的药物利用指数大于1,其余药物符合合理用药标准.结论 合理应用抗高血压药物,能够在一定程度上保证治疗效果,帮助患者稳定血压,提高患者的生存质量.
Clinical application of five kinds of antihypertensive drugs in department of cardiology
Objective To study and analyze the clinical application of five kinds of antihypertensive drugs in Department of cardiology. Methods In our hospital from January 2015 to December 2016 treated 100 cases of oral antihypertensive drugs in cardiovascular disease patients as the research object of this study, retrospective analysis of clinical data of patients, medication of patients, the system analysis of selected patients with medication, including patient name and the category, record the daily dose and the drug combination. Evaluation was made by using frequency index and index of utilization of drugs. The standard of rational drug use is drug utilization index (<1). Results After the corresponding analysis, the number of available urine drugs was 32 cases, the utilization rate was 32%. The number of use of beta blocking drugs was 28, with a utilization rate of 28%. The number of use cases of calcium antagonists was 20 cases, and the utilization rate was 20%. Angiotensin converting enzyme inhibitors were used in 14 cases, with a utilization rate of 14%. The use of angiotensin receptor Ⅱ blockers was 6 cases, with a utilization rate of 6%. Five of the three antihypertensive drugs were diuretic drugs, beta blockers and calcium antagonists. The highest frequency of use of metoprolol was 25%. The number of cases with furosemide was 13, and the frequency of medication was 13%. The number of drugs used in Extended Release Nifedipine Tablets was 12 cases, and the frequency was 12%. After the research, we can conclude that the combination of two or triple drugs is more effective in the combined use of hypertension. The utilization index of Hydrochlorothiazide Tablets and amlodipine tablets was greater than 1, and the other drugs met the standard of rational use. Conclusion The rational use of antihypertensive drugs can guarantee the effect of treatment to some extent, help patients to stabilize blood pressure, improve the quality of life of patients.

department of cardiologyantihypertensive drugsclinical effect

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浙江中医药大学附属富阳区第一医院 全科病区,浙江 杭州 311400

心内科 抗高血压药物 临床效果

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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