中国生化药物杂志2017,Vol.37Issue(8) :293-294,297.DOI:10.3969/j.issn.1005-1678.2017.08.124

心理干预联合阿仑膦酸钠、低分子肝素钙治疗老年骨质疏松性骨折效果观察

Observation on the effect of psychological intervention combined with alendronate sodium and low molecular heparin calcium on the treatment of senile osteoporotic fracture

楼慧君 李红娟
中国生化药物杂志2017,Vol.37Issue(8) :293-294,297.DOI:10.3969/j.issn.1005-1678.2017.08.124

心理干预联合阿仑膦酸钠、低分子肝素钙治疗老年骨质疏松性骨折效果观察

Observation on the effect of psychological intervention combined with alendronate sodium and low molecular heparin calcium on the treatment of senile osteoporotic fracture

楼慧君 1李红娟1
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作者信息

  • 1. 浙江省建德市第一人民医院 骨一科,浙江 建德 311600
  • 折叠

摘要

目的 观察心理干预联合阿仑膦酸钠、低分子肝素钙在治疗老年骨质疏松性骨折中的应用,评价其临床效果.方法 对2014年2月~2017年3月本院收治的82例骨质疏松性骨折老年患者的临床资料进行回顾性分析,采用数字表随机法分为参照组与试验组各41例,对其中参照组患者给予阿仑膦酸钠、低分子肝素钙治疗;试验组在参照组基础上联用心理护理干预,比较2组患者治疗情况.结果 于治疗前相比,2组患者治疗后骨密度(BMD)指数、骨痛评分均明显改善,且试验组改善效果显著优于参照组(P<0.05);此外,试验组治疗总有效率为95.12%(39/41)、并发症发生率为17.07%(7/41),参照组则分别为70.73%(29/41)、36.59%(15/41),2组差异均具有统计学意义(P<0.05).结论 心理干预联合阿仑膦酸钠、低分子肝素钙应用于治疗老年骨质疏松性骨折中效果显著,可有效改善患者临床症状,降低并发症的发生,具有临床应用与推广价值.

Abstract

Objective To observe the clinical effect of psychological intervention combined with alendronate and low molecular heparin calcium on the treatment of senile osteoporotic fracture. Methods From February 2014 to March 2017, clinical data of 82 elderly patients with osteoporotic fracture in the first people's hospital in Jiande were retrospectively analyzed. All the patients were randomly divided into the control group and the experimental group with 41 cases in each group. The control group patients were given alendronate sodium and low molecular heparin calcium; At this basis, the experimental group were received psychological nursing intervention. The effect in the two groups was compared. Results After treatment, bone mineral density (BMD) index and pain scores in the two groups were significantly improved. BMD and pain scores in the experimental group were significantly better than those in the control group (P<0.05). The total effective rate was 95.12% (39/41) and the complication rate was 17.07% (7/41) in the experimental group, while in the control group were respectively 70.73% (29/41), 36.59% (15/41), the differences were statistically significant (P<0.05). Conclusion Psychological intervention combined with alendronate sodium and low molecular heparin on the treatment of senile osteoporotic fracture has significant effect, can effectively improve the clinical symptoms of patients, reduce the incidence of complications, with clinical application value.

关键词

心理干预/阿仑膦酸钠/低分子肝素钙/老年/骨质疏松性骨折

Key words

psychological intervention/alendronate sodium/low molecular heparin calcium/elderly/osteoporotic fracture

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量4
参考文献量11
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