首页|布地奈德混悬液联合特布他林雾化液对胸外科手术VAP及康复的影响

布地奈德混悬液联合特布他林雾化液对胸外科手术VAP及康复的影响

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目的 探讨布地奈德混悬液联合特布他林雾化液对胸外科手术患者呼吸机相关性肺炎(VAP)及康复效果的影响.方法 选取宁海县第一医院2016年6月~2017年1月收治的55例胸外科手术患者为观察组,该组患者均采用布地奈德悬液联合特布他林雾化液进行雾化吸入.选取同期收治的40例采用传统雾化吸入的胸外科手术患者为对照组.比较2组术后的血气指标、VAP的发生率、机械通气以及住院时间等.结果 观察组术后3 d的白细胞、中性粒细胞、CRP与对照组的差异无统计学意义.观察组术后3 d的氧饱和度大于对照组,动脉氧气分压高于对照组,PaCO2低于对照组,差异有统计学意义(P<0.05).观察组术后的VAP低于对照组,机械通气时间短于对照组,住院时间短于对照组,差异有统计学意义(P<0.05).结论 布地奈德混悬液联合特布他林雾化液能够提高胸外科手术患者术后的雾化效果,减少术后VAP的发生,促进患者早日康复.
Effects of budesonide suspension combined with terbutaline on the VAP and rehabilitation of thoracic surgery
Objective To investigate the effect of budesonide suspension combined with terbutaline on the ventilator-associated pneumonia (VAP) and rehabilitation in patients undergoing thoracic surgery. Methods Fifty-five patients underwent thoracic surgery from June 2006 to January 2017 in our hospital. The patients were treated with budesonide suspension combined with terbutaline atomization solution for inhalation. Forty patients with thoracic surgery were selected as the control group. Comparison of the two groups after the blood gas indicators, the incidence of VAP, mechanical ventilation and hospital stay. Results There was no significant difference in white blood cells, neutrophils and CRP between the two groups.The oxygen saturation of the observation group was higher than that of the control group, the arterial oxygen partial pressure was higher than the control group, PaCO2 was lower than the control group, the difference was statistically significant (P<0.05). The VAP of the observation group was lower than that of the control group. The time of mechanical ventilation was shorter than that of the control group. The hospitalization time was shorter than that of the control group, the difference was statistically significant (P<0.05). Conclusion The combination of budesonide suspension and terbutaline atomization can improve the postoperative effect of thoracic surgery and reduce the incidence of postoperative VAP and promote the early rehabilitation of patients.

budesonideterbutalineinhalationdepartment of thoracic surgeryVAPrehabilitation

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宁海县第一医院 胸外科,浙江 宁波 315600

布地奈德混悬液 特布他林 雾化吸入 胸外科 VAP 康复

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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