首页|侵袭性牙周炎基础治疗中不同时机口服抗生素的短期疗效观察

侵袭性牙周炎基础治疗中不同时机口服抗生素的短期疗效观察

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目的 探究侵袭性牙周炎(agressive periodontitis,AgP)基础治疗中不同时机联合应用抗生素的短期临床疗效及应用价值.方法 选择2015年11月~2017年3月到江油九〇三医院治疗的78例AgP患者为研究对象,采用随机数字法将患者分为观察组和对照组,各39例.在给予基础治疗的基础上,观察组在洁治后服用阿莫西林和甲硝唑,对照组在刮治后服用阿莫西林和甲硝唑.观察并比较基础治疗前后患者菌斑情况以及治疗8周后2组患者的治疗效果.结果 2组患者基础治疗后菌斑情况较基础治疗前明显改善(P<0.05).2组患者探诊深度和附着丧失情况在治疗8周后比较差异无统计学意义.观察组的出血指数明显低于对照组.观察组在探诊深度7 mm位点与根分叉位点探诊深度幅度减少要明显优于对照组(P<0.05).结论 在基础治疗的基础上,服用抗生素对AgP患者有较好的治疗效果,其中洁治后服用抗生素的治疗效果优于刮治后服用抗生素,值得在临床上推广.
Observation on the short term effect of oral antibiotic at different times on the treatment of invasive periodontitis
Objective To explore the short-term effect of oral antibiotic at different times on the treatment of invasive periodontitis. Methods 78 patients with invasive periodontitis from November 2015 to March 2017 were enrolled in this study. Randomized method was used to divide the patients into the observation group and the control group, 39 cases in each group. On the basis of the basic treatment, the observation group were received amoxicillin and metronidazole after oral prophylaxis, the control group were received amoxicillin and metronidazole after subgingival scaling. The plaque status before and after the basic treatment and the efficacy in the two groups after 8 weeks were compared. Results The plaque in the two groups was significantly improved after basic treatment (P<0.05). There was no significant difference in the probing depth and the loss of attachment between the two groups. The bleeding index in the observation group was significantly lower than that in the control group (P <0.05). The probing depth in the observation group was significantly better than that in the control group (P<0.05). Conclusion On the basis of basic therapy, taking antibiotics has a better therapeutic effect on the patients with invasive periodontitis. Antibiotics is use after oral prophylaxis is better than it used after subgingival scaling, which is worthy to be popularized in clinical practice.

invasive periodontitisbasic treatmentantibiotics

畅词、杜霖

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江油九〇三医院 口腔科,四川 江油 621700

侵袭性牙周炎 基础治疗 抗生素

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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