首页|复方阿嗪米特、莫沙必利联合治疗老年胃肠疾病相关性消化不良疗效分析

复方阿嗪米特、莫沙必利联合治疗老年胃肠疾病相关性消化不良疗效分析

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目的 探究复方阿嗪米特+莫沙必利联合方案在老年胃肠疾病相关性消化不良治疗中的应用效果.方法 将2016年4月~2017年4月本院收治的116例老年胃肠疾病相关性消化不良患者随机分为观察组与对照组,每组58例.观察组纳入阿嗪米特+莫沙必利联合方案治疗患者,对照组纳入单用莫沙必利方案治疗患者,均治疗28 d.记录2组治疗前后消化不良症状总积分,依据治疗后症状积分缓解率评估临床疗效,计算2组不良反应发生率并行组间比较.结果 治疗前,2组消化不良症状总积分比较差异无统计学意义,2组消化不良症状总积分在有效疗程结束后均有不同程度降低,观察组降幅显著优于对照组(P<0.05).观察组治疗有效率为87.9%显著高于对照组60.3%(P<0.05).结论 复方阿嗪米特联合莫沙必利是治疗老年胃肠疾病相关性消化不良的有效方案,联合用药显著改善患者消化不良症状,提高患者生活质量,临床应用反馈良好,安全性可靠.
Analysis of curative effect of compound azinomide and mosapride in the treatment of senile gastrointestinal diseases associated with indigestion
Objective To explore the compound azintamide + mosapride application regimen in elderly patients with gastrointestinal diseases and associated dyspepsia in the treatment. Methods 116 cases of elderly patients with gastrointestinal disease associated dyspepsia patients treated in our hospital from April 2016 to April 2017 were randomly divided into observation group and control group, with 58 cases in each group. The observation group was treated with azintamide + mosapride,the control group was treated with mosapride,the two groups were treated for 28 d .The total score of dyspeptic symptoms before and after treatment in two groups was recorded, and the clinical symptoms were evaluated according to the remission rate of symptom scores. The incidence of adverse reactions in the two groups was calculated and compared between the two groups. Results There was no significant difference in total scores of dyspepsia symptoms between two groups before treatment. The total score of the two groups of dyspepsia symptoms decreased in different degrees after the end of the effective course,the observation group was significantly better than the control group (P<0.05). The effective rate of the observation group was 87.9%, which was significantly higher than that of the control group (60.3%) (P<0.05). Conclusion Compound azintamide combined with Mosapride is effective in the treatment of gastrointestinal diseases associated dyspepsia in elderly patients, combination therapy significantly improved in patients with dyspeptic symptoms, improve the quality of life of patients, clinical application of feedback is good, safe and reliable.

compound azintamidemosaprideelderly gastrointestinal diseases and indigestion

吴浩、唐啸

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武汉市东湖医院 内六科,湖北 武汉 430074

武汉科技大学附属天佑医院医学影像科,湖北 武汉 430064

复方阿嗪米特 莫沙必利 老年胃肠疾病相关性消化不良

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(8)
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