注射用骨瓜提取物治疗膝关节骨关节炎的疗效观察
Clinical observation of Cervus and Cucumis Polypeptide for Injection in the treatment of knee osteoarthritis
李顺达 1徐鲁 1王臻 1何勇 1张钰山1
作者信息
- 1. 浙江省新昌县人民医院 骨科,浙江 绍兴 312500
- 折叠
摘要
目的 研究分析注射用骨瓜提取物治疗膝关节骨关节炎的疗效观察.方法 选取浙江省新昌县人民医院2015年2月～2017年5月收治的100例膝关节骨关节炎患者为研究对象,随机分为对照组和实验组,每组患者各为50例.对照组患者给予口服氨基葡萄糖胶囊治疗,实验组缓和进行注射用骨瓜提取物治疗,250 mL生理盐水加上25 g骨瓜提取物,口服尼美利舒胶囊.2组患者的治疗时间均为1个月.比较分析实验组与对照组患者的治疗效果.结果 经过对应的治疗后,实验组患者中,4例患者无效,20例好转,26例治愈.对照组患者中,13例患者无效.可得,实验组患者的治疗有效率为92.0％显著高于对照组,具有统计学意义(P<0.05).实验组患者的膝关节液的IL-1为(8.01±1.72),对照组患者的膝关节液的IL-1为(7.08±0.97).可得,实验组患者膝关节液IL-1水平显著高于对照组,具有统计学差异(P<0.05).结论 注射用骨瓜提取物治疗膝关节骨关节炎临床效果较好,能够显著提高治疗有效率.
Abstract
Objective To investigate and analyze the efficacy of Cervus and Cucumis Polypeptide for Injection in the treatment of osteoarthritis of the knee. Methods 100 patients with osteoarthritis of knee joint treated in Xinchang people's hospital from February 2015 to May 2017 were selected and randomly divided into the control group and the experimental group, with 50 patients in each group. The control group were treated with oral glucosamine capsules in the treatment of the experimental group, Cervus and Cucumis Polypeptide for Injection palliative treatment, 250 mL saline plus 25g guguatiquwu, oral Nimeilishu capsule. The treatment time of the 2 groups was one month. The therapeutic effects of the experimental group and the control group were compared and analyzed. Results After the corresponding treatment, 4 patients in the experimental group were invalid, 20 cases were effective, and 26 cases were effective. In the control group, 13 patients were ineffective. The effective rate of the experimental group was 92％, which was significantly higher than that of the control group (P<0.05). The IL-1 of the knee joint fluid in the experimental group was (8.01±1.72), and the IL-1 of the knee fluid in the control group was (7.08±0.97). The level of IL-1 in the knee joint fluid of the experimental group was significantly higher than that of the control group, with statistical difference (P<0.05). Conclusion Cervus and Cucumis Polypeptide for Injection is effective in the treatment of osteoarthritis of the knee, and can significantly improve the efficiency of treatment,.
关键词
骨瓜提取物/膝关节骨关节炎/临床效果Key words
bone and melon extract/knee osteoarthritis/clinical effect引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据