中药心脑血脉宁联合他汀类药物对脑梗死患者颈动脉粥样硬化斑块的影响
Xinnaoxuemianning Combined with Statins on Carotid Atherosclerotic Plaque in Patients with Cerebral Infarction
沈卫 1林东2
作者信息
- 1. 浙江省平阳县第一人民医院 药剂科,浙江 温州 325400
- 2. 浙江省平阳县中医院 中医内科,浙江 温州 325400
- 折叠
摘要
目的 分析中药心脑血脉宁联合他汀类药物对脑梗死患者颈动脉粥样硬化斑块的影响.方法 选取180例脑梗死患者并按随机数字表法分为观察组(90例)与对照组(90例),对照组给予阿托伐他汀钙片,观察组联合心脑血脉宁,分别于治疗前后对患者颈动脉粥样硬化斑块的变化情况、预后进行评价,并统计不良反应发生率.结果 治疗前2组颈动脉粥样硬化斑块及中医症候积分、神经功能缺损评分对比无差异;治疗后上述指标均显著改善,且观察组改善幅度优于对照组;同时,观察组不良反应发生率(5.56％)低于对照组(13.33％),差异具有统计学意义(P<0.05).结论 心脑血脉宁能减少脑梗死患者颈动脉粥样硬化斑块面积,纠正不稳定性斑块.
Abstract
Objective To investigate the effects of Xinnaoxuemianning combined with statins on carotid atherosclerotic plaque in patients with cerebral infarction. Methods 180 cerebral infarction patients were divided into the observation group (90cases) and the control group (90cases) by random number table method. The control group was given atorvastatin calcium tablets and the observation group was given additionally Xinnaoxuemianning. The changes and prognosis of carotid atherosclerotic plaques were evaluated before and after treatment, and the incidence of adverse reactions was counted. Results There were no differences in the carotid atherosclerotic plaque, TCM syndrome score and neurological deficit severity between the two groups before treatment. After treatment, the above indexes were significantly improved, and the increasing degree of the observation group was better than that of the control group. The incidence rate of adverse reactions was lower in the observation group than that in the control group (5.56％ vs.13.33％) (P<0.05). Conclusion Xinnaoxuemianning can reduce the carotid atherosclerotic plaque area and correct the unstable plaques in patients with cerebral infarction.
关键词
心脑血脉宁/他汀类药物/脑梗死/颈动脉粥样硬化斑块Key words
Xinnaoxuemianning/statins/cerebral infarction/carotid atherosclerotic plaque引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据