中国生化药物杂志2017,Vol.37Issue(9) :89-90,93.DOI:10.3969/j.issn.1005-1678.2017.09.035

银杏叶提取物对缺血性脑卒中疗效及血清超氧化物歧化酶和丙二醛影响分析

Effect of Ginkgo biloba extract on ischemic stroke and its influence on serum superoxide dismutase and malondialdehyde

王利敏 王青华
中国生化药物杂志2017,Vol.37Issue(9) :89-90,93.DOI:10.3969/j.issn.1005-1678.2017.09.035

银杏叶提取物对缺血性脑卒中疗效及血清超氧化物歧化酶和丙二醛影响分析

Effect of Ginkgo biloba extract on ischemic stroke and its influence on serum superoxide dismutase and malondialdehyde

王利敏 1王青华1
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作者信息

  • 1. 浙江中医药大学附属湖州市中医院 药剂科,浙江 湖州 313000
  • 折叠

摘要

目的 分析银杏叶提取物对缺血性脑卒中治疗疗效及对血清超氧化物歧化酶(SOD)和丙二醛(MDA)的影响.方法 146例缺血性脑卒中者分成2组,对照组和观察组2组均常规治疗,观察组另加服银杏叶提取物片.结果 治疗后,观察组临床疗效、SOD、MDA和ET-1、血液流变学、NIHSS评分、Barthel指数均优于对照组(P<0.05).不良反应方面,差异无统计学意义.结论 银杏叶提取物可提高缺血性脑卒中治疗疗效,调节相关因子水平.

Abstract

Objective To analyze the effect of Ginkgo biloba extract on ischemic stroke and its influence on serum superoxide dismutase(SOD) and malondialdehyde(MDA). Methods 146 patients with ischemic stroke were divided into two groups. The two groups were treated routinely and one group plus Ginkgo biloba extract. Results After treatment,the clinical efficacy,SOD,MDA and ET-1 level,hemorheology,NIHSS scores and Barthel index of observation group was better than that in the control group(P<0.05).Difference of adverse reactions were not statistically significant. Conclusion Ginkgo biloba extract can improve the therapeutic effect of ischemic stroke and adjust the level of related factors.

关键词

银杏叶提取物/缺血性脑卒中/超氧化物歧化酶/丙二醛

Key words

ginkgo biloba extract/ischemic stroke/serum superoxide dismutase/malondialdehyde

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量2
参考文献量7
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