首页|卡前列素氨丁三醇注射液联合缩宫素对妊娠晚期瘢痕子宫产后出血的影响

卡前列素氨丁三醇注射液联合缩宫素对妊娠晚期瘢痕子宫产后出血的影响

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目的 探讨卡前列素氨丁三醇注射液联合缩宫素对妊娠晚期瘢痕子宫产后出血的影响,为卡前列素氨丁三醇注射液联合缩宫素的应用提供理论依据.方法 选用2015年5月~2017年5月期间在北京市第六医院进行药物治疗的52例妊娠晚期瘢痕子宫产后出血患者作为此次研究对象,均分为对照组与观察组.对照组应用缩宫素治疗,观察值给予卡前列素氨丁三醇注射液联合缩宫素治疗,对比分析2组患者治疗过程中的产后出血量、产后出血发生率.结果 观察组患者术中出血量、术后2 h、24 h出血量显著低于对照组,差异有统计学意义(P<0.05);观察组患者的产后出血发生率为3.85%,显著低于对照组的11.54%,差异有统计学意义(P<0.05).结论 卡前列素氨丁三醇注射液联合缩宫素治疗妊娠晚期瘢痕子宫产后出血,疗效显著,可降低产后出血率和出血量,值得推广应用.
Effect of prostaglandin tromethamine injection combined with oxytocin on postpartum hemorrhage of scarred uterus in late pregnancy
Objective To investigate the effect of carboprost tromethamine combined with oxytocin on postpartum hemorrhage of scarred uterus in late pregnancy, and to provide theoretical basis for the application of carboprost tromethamine combined with oxytocin. Methods From May 2015 to May 2017, 52 pregnant woman with postpartum hemorrhage with scarred uterus in late pregnancy in the sixth hospital in Beijing were divided into the control group and the observation group. The control group was treated with oxytocin, and the observed value was treated with progesterone tromethamine injection and oxytocin. Postpartum hemorrhage, the incidence of postpartum hemorrhage in the two groups were compared. Results The intraoperative blood loss, postoperative 2 h and postoperative 24 h bleeding in the observation group were significantly lower than those in the control group, the difference was statistically significant (P<0.05). The incidence of postpartum hemorrhage in the observation group was 3.85%, significantly lower than 11.54% in the control group, the difference was statistically significant (P<0.05). Conclusion carboprost tromethamine combined with oxytocin in the treatment of postpartum hemorrhage in the pregnant woman with scarred uterus in late pregnancy is effective and can reduce the rate of postpartum hemorrhage and the amount of bleeding, so it is worthy of popularization and application.

carboprost tromethamineoxytocinlate pregnancyscarred uterinepostpartum hemorrhage

张建梅

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北京市第六医院,北京 100083

卡前列素氨丁三醇注射液 缩宫素 妊娠晚期 瘢痕子宫 产后出血

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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