中国生化药物杂志2017,Vol.37Issue(9) :184-185,187.DOI:10.3969/j.issn.1005-1678.2017.09.079

头孢他啶在手术室干预中的效果对比观察及对干预质量的影响研究

Comparative study on the effect of ceftazidime in the intervention of operating room and its effect on intervention quality

臧青梅 李圆 阮爱娟 严界蓉
中国生化药物杂志2017,Vol.37Issue(9) :184-185,187.DOI:10.3969/j.issn.1005-1678.2017.09.079

头孢他啶在手术室干预中的效果对比观察及对干预质量的影响研究

Comparative study on the effect of ceftazidime in the intervention of operating room and its effect on intervention quality

臧青梅 1李圆 2阮爱娟 1严界蓉1
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作者信息

  • 1. 杭州师范大学附属医院 手术室,浙江 杭州 310015
  • 2. 杭州师范大学附属医院 耳鼻咽喉头颈外科,浙江 杭州 310015
  • 折叠

摘要

目的 探讨头孢他啶在手术室干预中的效果对比观察及对干预质量的影响.方法 选取2016年5月~2017年5月杭州师范大学附属医院收治的头颅患者366例,随机分为2组,对照组(n=184)进行开颅手术治疗,研究组(n=182)在手术过程当中预防性应用头孢他啶,对比2组患者治疗效果.结果 2组患者颅内感染发生情况对比方面,研究组患者颅内感染显著低于对照组(P<0.05);2组患者活菌数以及酶标值对比方面,研究组患者均显著低于对照组(P<0.05);2组患者干预质量对比方面,研究组患者的PCT(降钙素原)、CRP(C反应蛋白)、TNF-α(肿瘤坏死因子-α)以及白细胞计数均显著低于对照组(P<0.05).结论 头颅手术患者在手术室干预中预防使用头孢他啶,能够提高干预质量,降低感染发生率.

Abstract

Objective To investigate the effect of ceftidine in operating room intervention and its effect on the quality of intervention. Methods Select 2016 May to May 2017, hangzhou normal university affiliated hospital operating room of our hospital, 366 cases of patients with skull, 2 groups randomly divided into two groups, control group routine surgery, the team combined use of cephalosporins he totally, compared two groups of two groups patients therapeutic effect. Results The intracranial infection was significantly lower in the two groups than in the control group (P<0.05). In the two groups, the number of live bacteria and the comparison of enzyme value were significantly lower than that in the control group (P <0.05). Intervention quality compared two groups of 2 groups of patients, the team of PCT in patients with calcitonin (former) and CRP (CRP), TNF alpha (tumor necrosis factor alpha) and white blood cell count were significantly lower than control group (P< 0.05). Conclusion Children with oral ulcer treatment, the therapeutic effect of smecta ideal, clinical application shall be the head to prevent the use of cephalosporins in patients with surgical intervention in the operating room he totally, can improve the quality of intervention, reduce the incidence of infection.

关键词

头孢他啶/预防应用/头颅手术

Key words

ceftazidime/prophylacticuse/craniotomy

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
参考文献量5
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