甲氨喋呤联合清宫术治疗剖宫产瘢痕妊娠的临床疗效及对患者HCG影响
Clinical effect of methotrexate combined with dilatation and curettage treatment on the treatment of cesarean section scar pregnancy and the effect on HCG
陈正雯 1金巧丹 1祁锋 1柴泽英1
作者信息
- 1. 浙江省台州医院 妇产科,浙江 台州 317000
- 折叠
摘要
目的 探讨甲氨喋呤联合清宫术治疗剖宫产瘢痕妊娠的临床治疗效果及对患者HCG(绒毛膜促性腺激素)的影响.方法 选取2016年1月～2017年3月浙江省台州医院收治的剖宫产瘢痕妊娠患者130例,随机分为2组,对照组应用清宫术治疗,研究组予以清宫术联合甲氨喋呤治疗,对比2组患者治疗效果及对HCG的影响.结果 研究组患者的有效率显著高于对照组(P<0.05);治疗前2组患者的HCG水平无显著差异,治疗后研究组各个时间点HCG水平均显著低于对照组(P<0.05).结论 剖宫产瘢痕妊娠患者联合应用甲氨喋呤以及清宫术治疗,有利于提高治疗效果,减少手术出血量以及住院时间,降低HCG水平.
Abstract
Objective To investigate the clinical effect of methotrexate combined with dilatation and curettage on the treatment of cesarean section scar pregnancy and the effect on HCG (chorionic gonadotropin). Methods 130 cases with cesarean section scar pregnancy admitted in Taizhou hospital from January 2016 to March 2017 were randomly divided into two groups. The control group wasreceived dilatation and curettage. The study group was given methotrexate combined with dilatation and curettage.The effect and the influence to HCG in the two groups were compared. Results The effective rate in the study group was significantly higher than that in the control group (P<0.05). There was no significant difference in HCG level between the two groups before treatment. The levels of HCG in the study group were significantly lower than that in the control group (P<0.05). Conclusion Methotrexate combined with curettage on the treatment of cesarean scar pregnancy, can improve the therapeutic effect, reduce postoperative bleeding and hospitalization time, reduce the level of HCG.
关键词
甲氨喋呤/清宫术/剖宫产瘢痕妊娠/绒毛膜促性腺激素Key words
methotrexate/dilatation and curettage/cesarean scar pregnancy/human chorionic gonadotropin引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据