首页|心理干预联合吉非替尼术前化疗对局限性肺切除术后老年非小细胞肺癌患者的疗效影响研究

心理干预联合吉非替尼术前化疗对局限性肺切除术后老年非小细胞肺癌患者的疗效影响研究

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目的 探讨心理干预、吉非替尼联合用于老年非小细胞肺癌患者局限性肺切除手术前临床疗效.方法 对照组老年非小细胞肺癌患者均接受局限性肺切除术治疗,术前给予吉非替尼化疗;研究组在对照组基础上于术前化疗期间加用心理干预.结果 研究组手术切除率93.55%,对照组手术切除率74.19%,2组差异有统计学意义(P<0.05);研究组转移率(3.23%)、复发率(3.23%)均显著低于对照组转移率(19.35%)、复发率(16.13%),研究组1年生存率(80.65%)显著高于对照组(64.52%),2组差异有统计学意义(P<0.05).结论 在常规术前应用吉非替尼联合局限性切除手术治疗基础上,对老年非小细胞肺癌患者加用心理干预措施可使其获得更为理想的疗效、预后.
Study on the effect of psychological intervention combined with preoperative chemotherapy with gefitinib on elderly patients with non-small cell lung cancer after localized resection of lung cancer
Objective To investigate the clinical efficacy of psychological intervention and gefitinib in the treatment of elderly patients with non-small cell lung cancer with limited pulmonary resection. Methods The control group were all treated with limited pulmonary resection. Preoperative chemotherapy was given to gefitinib. The study group was given psychological intervention during the preoperative chemotherapy on the basis of the control group. Results The resection rate in the study group was 93.55%, while in the control group was 74.19%, the difference in the two groups was statistically significant(P<0.05). The transfer rate was 3.23% and the recurrence rate was 3.23% in the control group, which was significantly lower than those in the control group the transfer rate of 19.35%, the recurrence rate of 16.13%. 1 years survival rate in the study group 80.65% was significantly higher than that in the control group 64.52%, the difference was statistically significant(P<0.05). Conclusion On the basis of routine preoperative application of gefitinib combined with local excision treatment, the elderly patients with non-small cell lung cancer with psychological intervention measures can make them achieve more ideal effect and prognosis.

non-small cell lung cancerlocalized resection of the lunggefitinibpsychological intervention

魏晔、赖俊美、冯娅青

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丽水市中心医院 心胸外科,浙江 丽水 323000

丽水市中心医院 肿瘤内科,浙江 丽水 323000

非小细胞肺癌 局限性肺切除术 吉非替尼 心理干预

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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