雷贝拉唑治疗胃溃疡的临床观察
Clinical observation of rabeprazole in the treatment of gastric ulcer
徐芳1
作者信息
- 1. 丽水市人民医院 消化内科,浙江 丽水 323000
- 折叠
摘要
目的 探讨雷贝拉唑治疗胃溃疡的临床效果.方法 此次依不同治疗方案将2015年1月～2017年3月于本院诊治的胃溃疡患者120例分组为:对照组用阿莫西林+克拉霉素+奥美拉唑治疗,观察组用阿莫西林+克拉霉素+雷贝拉唑治疗;详细观察2组患者治疗前后临床症状评分变化情况、IL-2/IL-6/CRP水平变化情况、不良反应发生情况,并将所获相关数据作对比分析.结果 阿莫西林+克拉霉素+雷贝拉唑(观察组)治疗胃溃疡的效果优于阿莫西林+克拉霉素+奥美拉唑(对照组)治疗效果,患者临床症状评分变化情况优于对照组、IL-2/IL-6/CRP水平变化情况优于对照组,差异有统计学意义(P<0.05);2组患者不良反应发生率比较,差异无统计学意义.结论 胃溃疡患者选择阿莫西林+克拉霉素+雷贝拉唑治疗的效果显著,可充分改善患者临床症状、IL-2/IL-6/CRP水平,并不会提高不良反应发生率,值得临床上广泛用来治疗胃溃疡患者.
Abstract
Objective To investigate the clinical effect of Bella in the treatment of gastric ulcer. Methods According to the different treatment methods will be January 2015-2017 year in March in our hospital 120 cases of patients with gastric ulcer group: control group was treated with amoxicillin + clarithromycin + omeprazole treatment, the observation group used amoxicillin + clarithromycin + ray Bela with before and after treatment; the two groups were observed for clinical symptom score changes, the level of IL-2/IL-6/CRP the incidence of adverse reactions, and the relevant data for comparative analysis. Results Amoxicillin + clarithromycin + ray was Bella (observation group) in the treatment of gastric ulcer is better than omeprazole + amoxicillin + clarithromycin (control group) treatment, clinical symptoms score changes better than the control group, IL-2/IL-6/CRP levels than the control group, the difference was statistically significant (P<0.05); two groups of patients the adverse reaction rate comparison, the difference was not statistically significant. Conclusion The gastric ulcer patients choose amoxicillin + clarithromycin + ray Bella with significant curative effect, can improve the clinical symptoms and IL-2/IL-6/CRP level of patients, and will not increase the incidence of adverse reactions, it is worthy of widely used in the treatment of patients with gastric ulcer.
关键词
雷贝拉唑/胃溃疡/临床疗效Key words
rabeprazole/gastric ulcer/clinical efficacy引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据