首页|唑来膦酸治疗骨质疏松性椎体压缩骨折PKP术后应用研究

唑来膦酸治疗骨质疏松性椎体压缩骨折PKP术后应用研究

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目的 探讨唑来膦酸治疗骨质疏松性椎体压缩骨折PKP术后应用效果.方法 依不同治疗方式将2015年1月~2017年1月于西安市红会医院诊治并行骨质疏松性椎体压缩骨折PKP术后患者80例分为2组,对照组患者术后不用唑来膦酸治疗,观察组患者术后用唑来膦酸治疗;比较2组患者治疗效果及不良反应发生率.结果 观察组治疗效果优于对照组,患者临床症状改善情况优于对照组,患者不良反应发生率低于对照组,组间比较差异有统计学意义(P<0.05).结论 骨质疏松性椎体压缩骨折PKP术后患者用唑来膦酸治疗效果显著,可有效改善患者临床症状、不良反应少,值得临床上广泛用于骨质疏松性椎体压缩骨折PKP术后者.
Study on the application of zoledronic acid in the treatment of osteoporotic vertebral compression fractures with PKP
Objective To investigate the application effect of zoledronic acid on PKP after osteoporotic vertebral compression fractures. Methods According to different treatment methods, 80 cases of patients from January 2015 to January 2017 in Xi'an City, Hong hui Red Cross hospital diagnosis and treatment of osteoporotic vertebral compression fractures parallel PKP were divided into two groups. The patients in the control group were not treated with zoledronic acid, and the patients in the observation group were treated with zoledronic acid.The treatment effect and adverse reaction rate were compared between two groups. Results The treatment effect of the observation group was better than that of the control group, and the improvement of the clinical symptoms of the observation group was better than that of the control group, and the incidence of adverse reactions was lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion The effect of zoledronic acid treatment on osteoporotic vertebral compression fractures after PKP is remarkable, which can effectively improve the patients' clinical symptoms, less adverse reactions, is widely used in clinical osteoporotic vertebral compression fractures after PKP holds.

osteoporosisvertebral compression fracturePKP holds the operationazole to phosphonic acid

刘洋、李辉、贺欣、李厚坤、张嘉南、张斌、宋涛、郝定均

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西安市红会医院 骨科, 陕西 西安 710054

骨质疏松症 椎体压缩骨折 PKP术 唑来膦酸

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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