唑来膦酸治疗骨质疏松性椎体压缩骨折PKP术后应用研究
Study on the application of zoledronic acid in the treatment of osteoporotic vertebral compression fractures with PKP
刘洋 1李辉 1贺欣 1李厚坤 1张嘉南 1张斌 1宋涛 1郝定均1
作者信息
- 1. 西安市红会医院 骨科, 陕西 西安 710054
- 折叠
摘要
目的 探讨唑来膦酸治疗骨质疏松性椎体压缩骨折PKP术后应用效果.方法 依不同治疗方式将2015年1月～2017年1月于西安市红会医院诊治并行骨质疏松性椎体压缩骨折PKP术后患者80例分为2组,对照组患者术后不用唑来膦酸治疗,观察组患者术后用唑来膦酸治疗;比较2组患者治疗效果及不良反应发生率.结果 观察组治疗效果优于对照组,患者临床症状改善情况优于对照组,患者不良反应发生率低于对照组,组间比较差异有统计学意义(P<0.05).结论 骨质疏松性椎体压缩骨折PKP术后患者用唑来膦酸治疗效果显著,可有效改善患者临床症状、不良反应少,值得临床上广泛用于骨质疏松性椎体压缩骨折PKP术后者.
Abstract
Objective To investigate the application effect of zoledronic acid on PKP after osteoporotic vertebral compression fractures. Methods According to different treatment methods, 80 cases of patients from January 2015 to January 2017 in Xi'an City, Hong hui Red Cross hospital diagnosis and treatment of osteoporotic vertebral compression fractures parallel PKP were divided into two groups. The patients in the control group were not treated with zoledronic acid, and the patients in the observation group were treated with zoledronic acid.The treatment effect and adverse reaction rate were compared between two groups. Results The treatment effect of the observation group was better than that of the control group, and the improvement of the clinical symptoms of the observation group was better than that of the control group, and the incidence of adverse reactions was lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion The effect of zoledronic acid treatment on osteoporotic vertebral compression fractures after PKP is remarkable, which can effectively improve the patients' clinical symptoms, less adverse reactions, is widely used in clinical osteoporotic vertebral compression fractures after PKP holds.
关键词
骨质疏松症/椎体压缩骨折/PKP术/唑来膦酸Key words
osteoporosis/vertebral compression fracture/PKP holds the operation/azole to phosphonic acid引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据