首页|优甲乐干预131I治疗甲亢后早发甲减的观察

优甲乐干预131I治疗甲亢后早发甲减的观察

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目的 观察优甲乐干预131I治疗甲亢后早发甲减的影响.方法 选取2014年3月~2016年4月本院收治的200例甲亢患者为此次研究对象,按照随机数字表法分为研究组和对照组,各100例患者.所有患者在入院前均已接受了131I治疗,对照组患者常规治疗,研究组则在采用131I治疗后的第20天起开始连续使用优甲乐,连续使用20 d.对2组患者的甲状腺彩超、甲状腺显像、甲功以及摄碘率实验等进行检测和观察,并对2组患者在采用不同方式治疗后的临床疗效进行对比.结果 研究组患者与对照组患者在治疗后3、9及12个月的甲减发生率对比,研究组的甲减发生率均显著低于对照组,组间差异具有统计学意义(P<0.05).同时研究组患者与对照组的甲亢治愈率对比,研究组显著高于对照组,组间差异具有统计学意义(P<0.05).结论 在患者接受131I治疗后的早期为患者服用优甲乐可以在一定程度上减少甲减的发生,同时还能提高甲亢的首次治愈率,应用价值较高.
Observation of the effect of Jia Jia Le intervention on premature hypothyroidism after 131I treatment of hyperthyroidism
Objective To observe and analyze the euthyrox intervention effect of early hypothyroidism after 131I therapy for hyperthyroidism. Methods 200 cases of patients with hyperthyroidism in our hospital from March 2014 to April 2016 were selected as the object of the experiment needs, all the patients were randomly divided into two groups, respectively into study group and control group, two groups there are 100 patients. All patients before admission were accepted 131I treatment, control group received routine treatment, the study group was treated with 131I in twentieth days after start of continuous use of euthyrox, 20 days of continuous use, the two groups of patients with thyroid ultrasound, thyroid gland imaging, thyroid function and perturbation the rate of iodine was detected and observed. And the two groups of patients in the clinical efficacy of different after treatment were compared. Results The patients in the study group and the control group in 3 months after treatment, 9 months and 12 months the incidence of hypothyroidism were compared, research The incidence rate of hypothyroidism group was significantly lower than the control group, the differences between the groups were statistically significant (P<0.05). Patients in the study group and the control group at the same time, the cure rate of hyperthyroidism compared to the study group was significantly higher than that of control group, with statistical significance (P<0.05). Conclusion In patients with early after 131I treatment for patients taking euthyrox can to some extent reduce the occurrence of hypothyroidism, but also can improve the cure rate of hyperthyroidism for the first time, a higher application value.

hyperthyroidismEuthyrox131Iinterventionhypothyroidism

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湖州市中心医院 甲状腺外科,浙江 湖州 313000

甲亢 优甲乐 131I 干预 甲减

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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