摘要
目的 探究替吉奥联合奥沙利铂治疗晚期胃癌的临床效果与不良反应情况.方法 从2014年1月～2017年1月在本院接受治疗的晚期胃癌中,选取其中的88例作为样本,采用奇偶数分组法,随机分为对照组44例,观察组44例.对照组和观察组分别采用替吉奥治疗以及替吉奥联合奥沙利铂治疗,对比两种治疗方式的临床效果以及不良反应发生情况.结果 观察组的总治疗效果为91.0％,明显高于对照组的75.0％,差异有统计学意义(P<0.05),;观察组不良反应发生率为9.1％,对照组不良反应发生率为27.3％,,2组差异有有统计学意义(P<0.05).结论 替吉奥联合奥沙利铂应用于晚期胃癌的治疗中,临床效果显著,不良反应发生率低,安全性高,值得推广.
Abstract
Objective To explore the clinical effect and adverse effects of tiggio combined with oxaliplatin on the treatment of advanced gastric cancer. Methods From January 2014 to January 2017, 88 cases with advanced gastric cancer were selected as the samples in Yangling demonstration zone hospital. All the patients were randomly divided into the control group (n = 44) and the observation group (n = 44). The control group and the observation group were treated with tiggio and tiggio combined with oxaliplatin respectively, and the clinical effect and the occurrence of adverse reactions in the two groups was compared. Results The total effect in the observation group was 91.0％, which was significantly higher than that in the control group (75.0％), (P<0.05); The incidence of adverse reactions in the control group was 27.3％, while in the observation group was 9.1％ the difference was statistically significant(P<0.05). Conclusion Tiggio combined with oxaliplatin in the treatment of advanced gastric cancer, the clinical effect is significant, the incidence of adverse reactions is low, high security, worthy of promotion.
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